Mammalian cDNA
ABclonal Technology FCRL3 Rabbit pAb
This gene encodes a member of the immunoglobulin receptor superfamily and is one of several Fc receptor-like glycoproteins clustered on the long arm of chromosome 1. The encoded protein contains immunoreceptor-tyrosine activation motifs and immunoreceptor-tyrosine inhibitory motifs in its cytoplasmic domain and may play a role in regulation of the immune system. Mutations in this gene have been associated with rheumatoid arthritis, autoimmune thyroid disease, and systemic lupus erythematosus. Alternative splicing results in multiple transcript variants.
Abcam ZK 756326, non-peptide CCR8 chemokine receptor agonist, 10MG
MW 429.39 g/mol, Purity >99%. Non-peptide CCR8 chemokine receptor agonist (EC₅₀ = 245 nM). Demonstrates no agonist activity against CCR3, CXCR3, CXCR4 and CCR5. Desensitizes the receptor against CCL1 stimulation.
The product is subject to the following: Abcam Restricted Use Statement