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Fully sequenced samples of complimentary DNA synthesized from single-stranded, non-mammalian RNA. A wide variety of gene inserts are available. Ideal for use in gene cloning, as gene probes, and cDNA library in creation.
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An esterified form of protectin D1; an intermediate in the synthesis of protectin D1; reduces infarct area and volume and increases blood vessel density in the tissue surrounding the infarct in a rat model of MCAO-induced ischemic stroke
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Her3 also called ErbB3 is a type I membrane glycoprotein that is a member of the ErbB family of tyrosine kinase receptors Her3 is expressed in keratinocytes melanocytes skeletal muscle cells embryonic myoblasts and Schwann cells Monomeric Her3 serves as a low affinity receptor for the heregulins (HRG)
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Human Fc gamma RIIIA/CD16a Protein is a receptor for the Fc region of IgG Binds complexed or aggregated IgG and also monomeric IgG Mediates antibody-dependent cellular cytotoxicity (ADCC) and other antibody-dependent responses such as phagocytosis
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An SPM; produced from EPA by 15-LO via 15(S)-HpEPE and 15S-hydroxy, 5S-HpEPE intermediates in vitro and by isolated human M2 macrophages or PMN neutrophils under normoxic or hypoxic conditions; enhanced synthesis in M2 macrophage and neutrophil co-cultures, indicating transcellular biosynthesis by a potential 15-LO and 5-LO mechanism; has been found in mouse inflammatory exudates; increases efferocytosis of apoptotic neutrophils or sRBCs by human M2 macrophages under hypoxic conditions in vitro; inhibits zymosan A- and thrombin-induced increases in inflammatory exudate neutrophil infiltration in a mouse model of hemorrhagic peritonitis at 100 ng/animal; increases inflammatory exudate macrophage infiltration and efferocytosis of apoptotic neutrophils and/or RBCs in the same model
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CD93 has been shown critical roles in inflammatory and immune diseases CD93 silencing increased IL-6 and TSLP but not IL-33 levels in culture supernatants HDM-induced asthma mice showed significant airway hyperresponsiveness and inflammation with Th2 cytokine activation along with decreased CD93 expression in bronchial epithelial cells and lung homogenates but increased serum CD93 levels
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