General Cell Based Assays
Eurofins Discoverx PathHunter eXpress CHRM3 Total Internalization Assay, 10pl Kit. (93-0775E3CP5L)
The PathHunter CHRM3 Total Internalization eXpress kit provides an easy to-use cell based assay to study drug candidates (small molecules or biologics) affecting GPCR activation and internalization. This kit uses EFC technology to measure ligand-induced internalization of CHRM3 via detection of localization to the early endosome. The included cell line overexpresses ProLink-tagged CHRM3 and an EA-tagged early endosome protein. Upon ligand-induced receptor activation, resulting internalization of the CHRM3 receptor to the early endosome leads to production of EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Lonza Walkersville PowerFeed A Bas Powder Kit 10L
PowerFeedA Chemically Defined and Protein-free Powder Kit is a non-animal origin powder feed kit containing all compontent to produce 10L of liquid feed The PowerFeed A Chemically Defined and Protein-free Powder Feed is formulated to maximize cell growth using Lonza CHO cell culture media ProCHO 4 -5 and PowerCHO 2 This BioWhittaker Cell Culture Media is produced according to cGMP and labelled For Further Manufacturing (FFM) GMP Products are intended for research or further manufacturing use only THIS PRODUCT IS NOT INTENDED FOR DIRECT THERAPEUTIC USE IN HUMANS
Abcam MK886, Lipo x ygenase inhibitor, 10MG
MW 494.1 Da, Purity >98%. Potent 5-lipoxygenase activating protein inhibitor (FLAP) (IC₅₀ = 44 nM). Inhibits leukotriene biosynthesis (IC₅₀ = 2.5 nM) in vitro and tumor activity in vivo. Displays PPARα antagonist activity. Orally active in vivo.
The product is subject to the following: Abcam Restricted Use Statement
National Diagnostics HYDROGEN PEROXIDE ASSAY 1KT
Hydrogen Peroxide Assay Kit, Rapid, sensitive adn quantitative method for the determination of Hydrogen Peroxide in chemical and biological systems, 1KT
Indigo Biosciences Human Adrenoceptor Alpha 1A (ADRA1A) All-inclusive Cell-Based Luciferase Reporter Assay Kit, 96-well assay plate format
Eliminate weeks of cell culture while achieving superior sensitivity with reproducible results from this all-inclusive cell-based luciferase reporter assay. INDIGO’s Human Adrenoceptor Alpha 1A reporter assay allows you to quickly screen test samples to quantify functional activity, either agonist or antagonist, they may exert against ADRA1A. Kit includes cryopreserved reporter cells engineered to provide constitutive expression of the receptor, optimized media for use during cell thawing and in diluting test samples, reference agonist, Luciferase Detection Reagent, cell culture-ready assay plate, and detailed assay protocol. INDIGO’s unique Cryomite™ process provides exceptional cell viability post-thaw and INDIGO’s strict QA process means consistent results lot to lot (product quality data available upon request). This kit allows researchers to achieve superior sensitivity, clear, reproducible results, and eliminate weeks of cell culture work.
Meso Scale Discovery U-PLEX Mouse IP-10 ASY 25 PL
The Meso Scale Discovery U-PLEX Mouse IP-10 Assay is a multiplex immunoassay kit that enables simultaneous quantitative measurement of mouse interferon gamma-induced protein 10 (IP-10) in serum plasma and cell culture supernatants It utilizes electrochemiluminescent detection technology on patterned arrays for high sensitivity and broad dynamic range The assay requires 50 L or less sample volume and can be read on the MESO QuickPlex SQ 120 instrument The kit includes a 96-well plate coated with capture antibodies detection antibodies calibrators and ancillary reagents needed to run the assay
Eurofins Discoverx cAMP Hunter eXpress OPRD1 CHO-K1 GPCR Assay, 2-Plate Kit. (95-0108E2CP2M)
The cAMP Hunter OPRD1 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. DADLE, DPDPE) based activation of OPRD1 GPCR activity via detection of decreasing levels of intracellular cAMP. This product uses EFC technology. The cells overexpress wild type OPRD1, a naturally Gi/Go coupled GPCR. Upon activation of OPRD1, the decrease in levels of intracellular cAMP leads to a decreased signal from EFC when the cAMP detection kit is applied. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx PathHunter eXpress IFNRL1/IL10RB Dimerization Assay, 2pl Kit. (93-0993E3CP5M)
The PathHunter IFNRL1/IL10RB Dimerization eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting receptor-receptor interaction. This kit assesses ligand (e.g. IL-29) induced dimerization of IFNRL1/IL10RB receptors. This product uses EFC technology. The cell line included overexpresses IFNRL1 target protein fused to PK alongside IL10RB target protein fused to EA. Upon ligand-induced dimerization of IFNRL1/IL10RB, detectable EFC signal is produced. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Meso Scale Discovery U-PLEX Mouse IL-17A/F ASY
The Meso Scale Discovery U-PLEX Mouse IL-17A/F Assay is a multiplex immunoassay kit for quantifying mouse interleukin 17A and 17F in various biological matrices It uses electrochemiluminescence detection for high sensitivity and minimal cross-reactivity The assay requires 50 L or less sample volume and takes about 3 5 hours It includes a 96-well plate with capture antibodies detection antibodies with electrochemiluminescent labels calibrators and assay diluent enabling efficient and accurate measurement of IL-17A and IL-17F in mouse samples
Eurofins Discoverx PathHunter Human IL-2 (IL-2R (IL2RA/IL2RB/IL2RG)) Dimerization Cell-Based Assay Kit (U2OS)
The PathHunter Human IL-2 (IL-2R (IL2RA/IL2RB/IL2RG)) Stable Cell Line Dimerization Assay (U2OS) measures ligand-induced dimerization of IL2RB/IL2RG/IL2RA. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx PathHunter Human EDNRB Total GPCR Internalization Cell-Based Assay Kit (U2OS)
The PathHunter Human EDNRB Stable Cell Line Total GPCR Internalization Assay (U2OS) contains a stable clonal cell line used to measure EDNRB (GPCR) internalization via early-endosome localization. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx PathHunter Human HTR2C (5-HT2C) β-Arrestin Cell-Based Assay Kit (U2OS)
The PathHunter Human HTR2C(VNV) (5-HT2C) β-Arrestin Stable Cell Line Assay (U2OS) contains a stable clonal cell line used to measure HTR2C(VNV) (GPCR) activity via recruitment of β-Arrestin2. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx PathHunter Human p53 (TP53) Nuclear Translocation Cell-Based Assay Kit (U2OS)
The PathHunter Human p53 (TP53) Stable Cell Line Nuclear Translocation Assay (U2OS) contains a stable clonal cell line used to measure p53 DNA damage pathway activation via nuclear translocation of p53. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Revvity Health Sciences Inc HTRF Human AQ STING Binding Kit, 100,000 Assay Points
HTRF Human AQ STING Binding Kit, 100,000 Assay Points