General Cell Based Assays
Optimize Technologies EXP Discovery Kit - Contains 1 holder and 3 trap cartridge packs (total of 9 traps). Create your custom kit by choosing a holder (Direct Connect or In-Line) and any 3 of the cartridge configurations.
The patent-pending Hand-Tight EXP™ Trap Column is rated for use at 20,000+ psi (1,400+ bar). This unique design connects directly to any injection valve (with 10-32 threads) or in-line with 1/16” stainless tubing for unparalleled convenience and efficiency. The EXP™ Cartridge System enables chemists to quickly remove detergents or salts which can affect the ionization process in MS work. This trapping technique can concentrate the sample directly on-line, allowing for increased recovery of precious sample material compared to off-line techniques. On-line trapping readily lends itself to automation for high-throughput analysis in UHPLC/MS applications. Free-Turn™ architecture allows the user to change cartridges by hand without breaking fluid connections on the holder inlet/outlet.
Eurofins Discoverx PathHunter Human IL-26 (IL20RA/IL10RB) Dimerization Cell-Based Assay Kit (U2OS)
The PathHunter Human IL-26 (IL20RA/IL10RB) Stable Cell Line Dimerization Assay (U2OS) measures ligand-induced dimerization of IL20RA/IL10RB. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx PathHunter Human 4-1BB (CD137) Signaling Cell-Based Assay Kit (U2OS)
The PathHunter Human 4-1BB (CD137) (NIK) Signaling Stable Cell Line Assay (U2OS) measures CD137 signal by activation-induced stabilization of NIK. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx PathHunter Human IL-1 alpha (IL1R1/IL1RAP) Dimerization Cell-Based Assay Kit (U2OS)
The PathHunter Human IL-1 alpha (IL1R1/IL1RAP) Stable Cell Line Dimerization Assay (U2OS) measures ligand-induced dimerization of IL1R1/IL1RAP. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
AURORA BIOLABS LLC Cov-19 NP Rabbit Binding Assay, 384 rxn
SARS-CoV-2 Nucleocapsid protein (NP) is one of the core components of SARS-CoV-2 virus. It forms a complex with viral genomic RNA in a helical symmetrical structure and plays a key role in the process of virus replication and assembly. Since NP is abundantly expressed during infection, it can be used as an important diagnostic marker for COVID-19 and also can be used as a potential drug target or developing vaccines. Terbium-labeled anti-Tag1 antibody serves as fluorescence donor, that binds to the His-Tagged NP. If a test rabbit antibody binds to NP, fluorescence- labeled anti-rabbit antibody (fluorescence acceptor) will be brought in close proximity with the fluorescence donor. Excitation of Terbium (340 nm) generates fluorescence resonance energy transfer (FRET) to the fluorescence-labeled acceptor, which consequently fluoresces at 665 nm (figure below). Thus, the test antibody binding to NP can be quantitively measured by calculation of the fluorescent ratio of 665 nm/620 nm.
Eurofins Discoverx PathHunter Human HTR5A (5-HT5A) β-Arrestin Cell-Based Assay Kit (U2OS)
The PathHunter Human HTR5A (5-HT5A) β-Arrestin Stable Cell Line Assay (U2OS) contains a stable clonal cell line used to measure HTR5A (GPCR) activity via recruitment of β-Arrestin2. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx PathHunter Human LTB4R Total GPCR Internalization Cell-Based Assay Kit (U2OS)
The PathHunter Human LTB4R Stable Cell Line Total GPCR Internalization Assay (U2OS) contains a stable clonal cell line used to measure LTB4R (GPCR) internalization via early-endosome localization. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx PathHunter Human PROKR1 β-Arrestin Cell-Based Assay Kit (CHO-K1)
The PathHunter Human PROKR1 β-Arrestin Stable Cell Line Assay (CHO-K1) contains a stable clonal cell line used to measure PROKR1 (GPCR) activity via recruitment of β-Arrestin2. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx PathHunter Human ADRB2 β-Arrestin Cell-Based Assay Kit (CHO-K1)
The PathHunter Human ADRB2 β-Arrestin Stable Cell Line Assay (CHO-K1) contains a stable clonal cell line used to measure ADRB2 (GPCR) activity via recruitment of β-Arrestin2. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx PathHunter Human F2RL3 β-Arrestin Cell-Based Assay Kit (CHO-K1)
The PathHunter Human F2RL3 β-Arrestin Stable Cell Line Assay (CHO-K1) contains a stable clonal cell line used to measure F2RL3 (GPCR) activity via recruitment of β-Arrestin2. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx PathHunter Human CCK1 (CCKAR) β-Arrestin Cell-Based Assay Kit (CHO-K1)
The PathHunter Human CCK1 (CCKAR) β-Arrestin Stable Cell Line Assay (CHO-K1) contains a stable clonal cell line used to measure CCKAR (GPCR) activity via recruitment of β-Arrestin2. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx PathHunter Human GPR143 β-Arrestin Cell-Based Assay Kit (CHO-K1)
The PathHunter Human GPR143 β-Arrestin Stable Cell Line Assay (CHO-K1) contains a stable clonal cell line used to measure GPR143 (GPCR) activity via recruitment of β-Arrestin2. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx PathHunter Human CTACK (CCR10) Activated GPCR Internalization Cell-Based Assay Kit (U2OS)
The PathHunter Human CTACK (CCR10) Stable Cell Line Activated GPCR Internalization Assay (U2OS) contains a stable clonal cell line used to measure CCR10 (GPCR) internalization via early-endosome localization. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
