General Cell Based Assays
Abcam TUNEL Assay Kit - HRP-DAB
TUNEL Assay Kit - HRP-DAB
The product is subject to the following: Abcam Restricted Use Statement
Eurofins Discoverx PathHunter eXpress PROKR1 CHO-K1 β-Arrestin GPCR Assay, 2-Plate Kit. (93-0303E2CP0M)
The PathHunter PROKR1 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. prokinectin, EG-VEGF) based activation of PROKR1 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged PROKR1 and EA-tagged β-Arrestin-2. Activation of PROKR1 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx PathHunter eXpress CCR9 CHO-K1 β-Arrestin GPCR Assay, 2-Plate Kit. (93-0296E2CP0M)
The PathHunter CCR9 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. CCL25) based activation of CCR9 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged CCR9 and EA-tagged β-Arrestin-2. Activation of CCR9 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx PathHunter eXpress GPR37L1 CHO-K1 β-Arrestin Orphan GPCR Assay, 10pl Kit. (93-0378E2ACP1L)
The PathHunter GPR37L1 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand based activation of GPR37L1 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged GPR37L1 and EA-tagged β-Arrestin-2. Activation of GPR37L1 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. This is an orphan receptor without a known ligand. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx PathHunter eXpress CALCRL-RAMP3 CHO-K1 β-Arrestin GPCR Assay, 2pl Kit. (93-0252E2CP0M)
The PathHunter CALCRL-RAMP3 (AM2) eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. adrenomedullin) based activation of CALCRL GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged CALCRL and EA-tagged β-Arrestin-2, along with untagged modulating protein RAMP3. Activation of CALCRL stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx PathHunter eXpress UTR2 CHO-K1 β-Arrestin GPCR Assay, 2-Plate Kit. (93-0283E2CP2M)
The PathHunter UTR2 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. urotensin) based activation of UTR2 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged UTR2 and EA-tagged β-Arrestin-2. Activation of UTR2 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx PathHunter eXpress NMU1R U2OS β-Arrestin GPCR Assay, 10-Plate Kit. (93-0232E3CP0L)
The PathHunter nMU1R eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. neuromedin U) based activation of nMU1R GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged nMU1R and EA-tagged β-Arrestin-2. Activation of nMU1R stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx PathHunter eXpress CRTH2 CHO-K1 β-Arrestin GPCR Assay, 2-Plate Kit. (93-0291E2CP2M)
The PathHunter CRTH2 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. prostaglandin D2) based activation of CRTH2 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged CRTH2 and EA-tagged β-Arrestin-2. Activation of CRTH2 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx PathHunter eXpress MC5R CHO-K1 β-Arrestin GPCR Assay, 2-Plate Kit. (93-0231E2CP2M)
The PathHunter MC5R eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. α-MSH) based activation of MC5R GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged MC5R and EA-tagged β-Arrestin-2. Activation of MC5R stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx PathHunter eXpress GPR143 CHO-K1 β-Arrestin Orphan GPCR Assay, 10-Plate Kit. (93-0362E2ACP1L)
The PathHunter GPR143 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand based activation of GPR143 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged GPR143 and EA-tagged β-Arrestin-2. Activation of GPR143 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. This is an orphan receptor without a known ligand. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Abcam Biotin Switch Assay Kit (S-Nitrosylation)
Biotin Switch Assay Kit (S-Nitrosylation)
The product is subject to the following: Abcam Restricted Use Statement
Eurofins Discoverx PathHunter eXpress CCR5 Activated GPCR Internalization Assay, 2-Plate Kit. (93-0653E3CP0M)
The PathHunter CCR5 Activated GPCR internalization eXpress kit provides an easy to-use cell based assay to study drug candidates (small molecules or biologics) affecting GPCR activation and internalization. This kit uses EFC technology to measure ligand-induced internalization of CCR5 via detection of localization to the early endosome. The included cell line overexpresses EA-tagged β-Arrestin-2 as well as a ProLink-tagged early endosome protein and untagged CCR5. Upon ligand-induced receptor activation, β-Arrestin-2 is recruited to the activated GPCR and the resulting CCR5-arrestin complex is internalized to the early endosome, leading to production of EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Meso Scale Discovery U-PLEX Mouse IL-13 ASY
The Meso Scale Discovery U-PLEX Mouse IL-13 Assay is an electrochemiluminescent immunoassay for the quantitative measurement of mouse interleukin 13 (IL-13) in serum plasma and cell culture supernatants The assay uses MSD s proprietary SECTOR Imager and provides high sensitivity a broad dynamic range and requires low sample volume The lower limit of detection is 0 04 pg/mL The assay can be multiplexed with other U-PLEX biomarkers for efficient and customizable biomarker profiling This IL-13 assay delivers rapid results in just 3 5 hours
Meso Scale Discovery R-PLEX Mouse C1q receptor ASY
The Meso Scale Discovery Mouse C1q Receptor R-PLEX Assay is a multiplex immunoassay that quantitatively measures C1q Receptor in mouse biological samples such as serum plasma and cell culture supernatants This assay utilizes electrochemiluminescence detection technology and provides high sensitivity broad dynamic range and requires low sample volume The assay requires an MSD instrument such as SECTOR Imager QuickPlex SQ 120 or QuickPlex SQ 120 The assay has a detection range of 50-100 000 pg/mL and the total assay time is approximately 3 5 hours This assay allows for the rapid reproducible quantification of C1q Receptor from mouse samples
Meso Scale Discovery R-PLEX Mouse Fractalkine ASY
The R-PLEX Mouse Fractalkine Assay from Meso Scale Discovery is a multiplex immunoassay that measures Fractalkine levels in mouse biological samples such as serum plasma and cell culture supernatants This assay utilizes MSD s electrochemiluminescence detection technology and is provided in a convenient 96-well plate format The assay has high sensitivity and wide dynamic range A proprietary diluent is provided for optimal sample dilution Each kit provides sufficient reagents to assay one 96-well plate This quantitative assay provides accurate and reproducible results with minimal sample volume requirements It offers a streamlined workflow and rapid results