General Cell Based Assays
Eurofins Discoverx PathHunter eXpress PTHR1 Activated GPCR Internalization Assay, 10pl Kit. (93-0770E3CP0L)
The PathHunter PTHR1 Activated GPCR internalization eXpress kit provides an easy to-use cell based assay to study drug candidates (small molecules or biologics) affecting GPCR activation and internalization. This kit uses EFC technology to measure ligand-induced internalization of PTHR1 via detection of localization to the early endosome. The included cell line overexpresses EA-tagged β-Arrestin-2 as well as a ProLink-tagged early endosome protein and untagged PTHR1. Upon ligand-induced receptor activation, β-Arrestin-2 is recruited to the activated GPCR and the resulting PTHR1-arrestin complex is internalized to the early endosome, leading to production of EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Meso Scale Discovery U-PLEX Human CA1 ASY
The Meso Scale Discovery U-PLEX Human CA1 Assay is a multiplex immunoassay kit for measuring CA1 in human serum plasma and cell culture supernatants It uses electrochemiluminescence detection for high sensitivity and rapid results The assay requires 50 L or less sample volume and is compatible with Meso Scale Discovery platforms It includes a 96-well plate with capture antibodies detection antibodies and necessary calibrators and controls This assay efficiently quantifies CA1 important in cancer and inflammatory diseases
Eurofins Discoverx PathHunter eXpress CCKAR Activated GPCR Internalization Assay, 2pl Kit. (93-0650E3CP5M)
The PathHunter CCKAR Activated GPCR internalization eXpress kit provides an easy to-use cell based assay to study drug candidates (small molecules or biologics) affecting GPCR activation and internalization. This kit uses EFC technology to measure ligand-induced internalization of CCKAR via detection of localization to the early endosome. The included cell line overexpresses EA-tagged β-Arrestin-2 as well as a ProLink-tagged early endosome protein and untagged CCKAR. Upon ligand-induced receptor activation, β-Arrestin-2 is recruited to the activated GPCR and the resulting CCKAR-arrestin complex is internalized to the early endosome, leading to production of EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Meso Scale Discovery R-PLEX Rat IL-6 ASY
The Meso Scale Discovery R-PLEX Rat IL-6 Assay is a multiplex immunoassay panel that allows simultaneous quantitative measurement of rat interleukin 6 (IL-6) in serum plasma and cell culture supernatants This assay uses electrochemiluminescence (ECL) detection technology and provides high sensitivity broad dynamic range and intra- and inter-assay precision with low sample volume requirements The assay requires 50 L or less of sample and has a testing time of 3 5 hours The lower limit of detection for rat IL-6 is 1 3 pg/mL This assay is for research use only and is not intended for diagnostic procedures It is available as a singleplex assay or as part of a multiplex panel
Eurofins Discoverx PathHunter IL7R/2RG Bioassay Kit, 10-Plate. (93-0997Y13-00082)
The PathHunter IL7R/IL2RG Dimerization Bioassay kit provides an easy-to-use cell based assay to measure drug potency and detect neutralizing antibodies. This bioassay assesses ligand (e.g. IL-7) induced dimerization of IL7R/IL2RG receptors. This product uses EFC technology. The cell line included overexpresses IL7R target protein fused to PK alongside IL2RG target protein fused to EA. Upon ligand-induced dimerization of IL7R/IL2RG, detectable EFC signal is produced. Bioassay kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, control agonist, detection reagent, and assay plates. For detailed product information, User manual and COA, visit www.discoverx.com/bioassay.
Eurofins Discoverx PathHunter eXpress mCCR6 CHO-K1 β-Arrestin GPCR Assay, 2-Plate Kit. (93-0694E2MCP2M)
The PathHunter mCCR6 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. CCL20/MIP-3α) based activation of mCCR6 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged mCCR6 and EA-tagged β-Arrestin-2. Activation of mCCR6 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. Please note that this product expresses the Mouse version of this protein. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx PathHunter eXpress OPN5 CHO-K1 β-Arrestin Orphan GPCR Assay, 10-Plate Kit. (93-0704E2CP1L)
The PathHunter OPN5 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand based activation of OPN5 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged OPN5 and EA-tagged β-Arrestin-2. Activation of OPN5 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx PathHunter eXpress ErbB2/ErbB4 Dimerization Assay, 10pl Kit. (93-0960E3CP5L)
The PathHunter ErbB2/ErbB4 Dimerization eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting receptor-receptor interaction. This kit assesses ligand (e.g. heregulin β-1) induced dimerization of ErbB2/ErbB4 receptors. This product uses EFC technology. The cell line included overexpresses ErbB2 target protein fused to PK alongside ErbB4 target protein fused to EA. Upon ligand-induced dimerization of ErbB2/ErbB4, detectable EFC signal is produced. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx PathHunter eXpress HCRTR2 Total GPCR Internalization Assay, 10pl Kit. (93-0730E3CP0L)
The PathHunter HCRTR2 Total GPCR internalization eXpress kit provides an easy to-use cell based assay to study drug candidates (small molecules or biologics) affecting GPCR activation and internalization. This kit uses EFC technology to measure ligand-induced internalization of HCRTR2 via detection of localization to the early endosome. The included cell line overexpresses ProLink-tagged HCRTR2 and an EA-tagged early endosome protein. Upon ligand-induced receptor activation, resulting internalization of the HCRTR2 receptor to the early endosome leads to production of EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx PathHunter eXpress CMKLR1 Activated GPCR Internalization Assay, 2pl Kit. (93-0720E3CP22M)
The PathHunter CMKLR1 Activated GPCR internalization eXpress kit provides an easy to-use cell based assay to study drug candidates (small molecules or biologics) affecting GPCR activation and internalization. This kit uses EFC technology to measure ligand-induced internalization of CMKLR1 via detection of localization to the early endosome. The included cell line overexpresses EA-tagged β-Arrestin-2 as well as a ProLink-tagged early endosome protein and untagged CMKLR1. Upon ligand-induced receptor activation, β-Arrestin-2 is recruited to the activated GPCR and the resulting CMKLR1-arrestin complex is internalized to the early endosome, leading to production of EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Biotang Inc Human Fructose-1,6-bisphosphate aldolase,FDA ELISA Kit, 96T
Human Fructose-1,6-bisphosphate aldolase,FDA ELISA Kit, 96T. Lead time of this kit is 1-2 weeks. Shipped by FedEx air. Storage: 2 - 8 C. Shelf Time: 6 months. Kit Experimental Time:< 2 hs. TSZELISA brand.
Sigma Aldrich Fine Chemicals Biosciences Autophagy Assay Kit sufficient for 200 fluorometric tests | 1KT
Autophagy Assay Kit sufficient for 200 fluorometric tests | 1KT
Eurofins Discoverx AssayComplete Cell Plating 27 Reagent, 100. (93-0563R27A)
AssayComplete Cell Plating 27 Reagent is an optimized cell plating reagent for use in plating of Eurofins DiscoverX cell lines for assays. This reagent was optimized for maximal cell health and ligand responsiveness during assays while eliminating hormones and growth components which may lead to increased basal activity. This product is provided as a bottle of 100 mL. Please refer to cell line specific datasheet to determine the recommended cell plating reagent. For detailed product information, User manual and datasheet, visit www.discoverx.com/reagents.
Meso Scale Discovery R-PLEX Human GAS-6/AXL-L ASY
The R-PLEX Human Gas6/Axl-L Assay Kit from Meso Scale Discovery is a multiplex immunoassay for measuring human Gas6 and Axl proteins in serum plasma and cell culture supernatants It uses electrochemiluminescence detection for high sensitivity and broad dynamic range with low sample volume The kit includes a 96-well plate with capture antibodies detection antibodies calibrators and necessary reagents It quantifies Gas6 and Axl crucial for cell survival proliferation migration and phagocytosis in 3 5 hours performing 39 tests in duplicate
Eurofins Discoverx PathHunter eXpress CXCR6 Total Internalization Assay, 10pl Kit. (93-0886E3CP0L)
The PathHunter CXCR6 Total Internalization eXpress kit provides an easy to-use cell based assay to study drug candidates (small molecules or biologics) affecting GPCR activation and internalization. This kit uses EFC technology to measure ligand-induced internalization of CXCR6 via detection of localization to the early endosome. The included cell line overexpresses ProLink-tagged CXCR6 and an EA-tagged early endosome protein. Upon ligand-induced receptor activation, resulting internalization of the CXCR6 receptor to the early endosome leads to production of EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.