General Cell Based Assays
Meso Scale Discovery U-PLEX Mouse IL-31 ASY 25 PL
The Meso Scale Discovery U-PLEX Mouse IL-31 Assay Kit is a multiplex immunoassay that measures mouse interleukin 31 (IL-31) in serum plasma and cell culture supernatants This assay uses electrochemiluminescence (ECL) detection technology and provides high sensitivity broad dynamic range and intra- and inter-assay precision The kit includes a plate coated with capture antibodies detection antibodies labeled with an ECL tag calibrator diluent wash buffer read buffer and a vial of lyophilized calibrator that must be reconstituted before use The assay can quantify mouse IL-31 concentrations between 1 5 and 10 000 pg/mL
Eurofins Discoverx cAMP Hunter eXpress MC4R CHO-K1 GPCR Assay, 2-Plate Kit. (95-0050E2CP2M)
The cAMP Hunter MC4R eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. α-melanocyte stimulating hormone) based activation of MC4R GPCR activity via detection of increasing levels of intracellular cAMP. This product uses EFC technology. The cells overexpress wild type MC4R, a naturally Gs coupled GPCR. Upon activation of MC4R, the increase in levels of intracellular cAMP leads to an increased signal from EFC when the cAMP detection kit is applied. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx PathHunter eXpress HTR2C U2OS β-Arrestin GPCR Assay, 10-Plate Kit. (93-0289E3CP3L)
The PathHunter HTR2C eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. serotonin) based activation of HTR2C GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged HTR2C and EA-tagged β-Arrestin-2. Activation of HTR2C stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Revvity Health Sciences Inc HTRF Human Phospho-H2AX (Ser139) Detection Kit, 50,000 Assay Points
HTRF Human Phospho-H2AX (Ser139) Detection Kit, 50,000 Assay Points
Cayman Chemical Adipogenesis Assay Kit
Cayman’s Adipogenesis Assay provides the reagents required for studying the induction and inhibition of adipogenesis in the established 3T3-L1 model, using the adipogenesis induction procedure. This kit can also be used to screen drug candidates involved in adipogenesis. The classic Oil Red O staining for lipid droplets is used in this kit as an indicator of the degree of adipogenesis, and can be quantified with a plate reader after the dye is conveniently extracted from the lipid droplet.
Meso Scale Discovery R-PLEX Human ALK ASY
The R-PLEX Human ALK Assay QuickPlex 5-PL Kit from Meso Scale Diagnostics is a multiplex immunoassay for measuring ALK in human serum plasma and cell culture supernatants It uses electrochemiluminescence detection on the QuickPlex SQ 120 instrument The assay takes about 3 hours and needs 12 5 L of sample with a detection range of 19 to 10 000 pg/mL The kit includes reagents for calibration controls diluent detection antibodies read buffer and plates with capture antibodies
Eurofins Discoverx PathHunter eXpress GALR1 CHO-K1 β-Arrestin GPCR Assay, 10-Plate Kit. (93-0228E2CP0L)
The PathHunter GALR1 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. galanin) based activation of GALR1 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged GALR1 and EA-tagged β-Arrestin-2. Activation of GALR1 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
PHYTO AB INC Actin Antibody Immunogen: AT3G12110 Background: Actin is an ancient conserved protein that is encoded by multiple isovariants in multi-cellular organisms. 150ug/EA
PhytoAB Inc. is a contract research organization and plant antibody R&D based services and products supplier. PhytoAB is privately owned company headquatered in the San Francisco Bay Area of California, USA. PhytoAB specializes in antibody production for plant scientic usage and customized services, focus on the current need of plant antibodies to assist the further investigation of the current booming results from deep genome sequencing and increasing protomics studies. We have specialized R&D and customer services teams to fulfill the needs of botany & plant sciences research and industry world wide with high quality, professional and cutting edge services, and offering complete products usage guidance and suggestions for related problem solutions.
Eurofins Discoverx PathHunter eXpress ACVRL1/ACVR2B Dimerization Assay, 2pl Kit. (93-0964E3CP22M)
The PathHunter ACVRL1/ACVR2B Dimerization eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting receptor-receptor interaction. This kit assesses ligand (e.g. GDF2/BMP9) induced dimerization of ACVRL1/ACVR2B receptors. This product uses EFC technology. The cell line included overexpresses ACVRL1 target protein fused to PK alongside ACVR2B target protein fused to EA. Upon ligand-induced dimerization of ACVRL1/ACVR2B, detectable EFC signal is produced. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Abcam ZLN005, PGC-1alpha transcriptional activator, 10MG
MW 250.34 Da, Purity >95%. PGC-1α transcriptional activator. Activates AMPK. Stimulates PGC-1α expression. Increases fat oxidation. Improves glucose and pyruvate tolerance. Increases insulin sensitivity. Shows antidiabetic effects in vivo. .
The product is subject to the following: Abcam Restricted Use Statement
Abcam Ko-143, BCRP inhibitor, 5MG
MW 469.6 Da. Potent, selective BCRP inhibitor (EC₅₀ values are 23 and 26 nM respectively for the export of mitoxantrone (ab145668, ab141041) and topotecan (ab120388) in cancer cell lines). Non-toxic fumitremorgin C (ab144258) analog. Shows chemopotentiating effects in vivo. .
The product is subject to the following: Abcam Restricted Use Statement
Eurofins Discoverx PathHunter eXpress IL2RB/IL2RG/IL2RA Dimerization Assay, 2pl Kit. (93-1003E3CP0M)
The PathHunter IL2RB/IL2RG/IL2RA Dimerization eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting receptor-receptor interaction. This kit assesses ligand (e.g. IL-2) induced dimerization of IL2RB/IL2RG/IL2RA receptors. This product uses EFC technology. The cell line included overexpresses IL2RB target protein fused to PK alongside IL2RG target protein fused to EA and untagged ILR2A. Upon ligand-induced dimerization of IL2RB/IL2RG/IL2RA, detectable EFC signal is produced. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx PathHunter eXpress FPRL1 CHO-K1 β-Arrestin GPCR Assay, 2-Plate Kit. (93-0319E2CP2M)
The PathHunter FPRL1 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. formylpeptides) based activation of FPRL1 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged FPRL1 and EA-tagged β-Arrestin-2. Activation of FPRL1 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx PathHunter eXpress GPR39 CHO-K1 β-Arrestin Orphan GPCR Assay, 2-Plate Kit. (93-0338E2CP1M)
The PathHunter GPR39 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand based activation of GPR39 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged GPR39 and EA-tagged β-Arrestin-2. Activation of GPR39 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. This is an orphan receptor without a known ligand. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Cayman Chemical cGAS MoncLNal ANTIBDYClo 300ug
Immunogen: Full length human recombinant protein • Host: Mouse, clone 5G10 • Species Reactivity: (+) Human cGAS • Application(s): WB, IF, and IP