General Cell Based Assays
Eurofins Discoverx PathHunter eXpress EDG4 CHO-K1 β-Arrestin GPCR Assay, 2-Plate Kit. (93-0255E2CP13M)
The PathHunter EDG4 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. LPA) based activation of EDG4 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged EDG4 and EA-tagged β-Arrestin-2. Activation of EDG4 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
S2 Media vLogiX ™ (VSTM) Kits, 50/box
vLogiX ™ (VTSM) is a non-selective and non-differential culture medium intended for the collection, conveyance, and storage of clinical specimens containing viral agents. vLogiX ™ (VTSM) is intended for use in standard laboratory procedures for culture and diagnostic assays. Each kit contains 1 tube of 3mL VTSM with borosilicate beads and 1 nasopharyngeal swab within a reclosable bag. Each box contains 50 kits.• Product meets ASM, CDC, and CLSI reference methods and performance criteria.• vLogiX™ should be used by trained professionals within a laboratory setting. • For in vitro diagnostic (IVD) use.• Product is not intended for use in the diagnosis or treatment of disease or other human conditions.
Abcam Metformin hydrochloride (mM/ml), AMPK activator, 100MM_ML
MW 165.63 g/mol, Purity >99%. AMPK activator. Antidiabetic and anticancer activity in vivo. Rapidly crosses the blood-brain barrier.
The product is subject to the following: Abcam Restricted Use Statement
Eurofins Discoverx PathHunter eXpress HCRTR1 CHO-K1 β-Arrestin GPCR Assay, 10-Plate Kit. (93-0258E2CP0L)
The PathHunter HCRTR1 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. orexin A) based activation of HCRTR1 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged HCRTR1 and EA-tagged β-Arrestin-2. Activation of HCRTR1 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Abcam Fructose-1,6-Bisphosphate Assay Kit (Fluorometic)
Fructose-1,6-Bisphosphate Assay Kit (Fluorometic)
The product is subject to the following: Abcam Restricted Use Statement
Eurofins Discoverx PathHunter eXpress MCHR2 U2OS β-Arrestin GPCR Assay, 10-Plate Kit. (93-0691E3CP5L)
The PathHunter MCHR2 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. MCH) based activation of MCHR2 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged MCHR2 and EA-tagged β-Arrestin-2. Activation of MCHR2 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Abcam Glucosylceramidase Activity Assay Kit (Fluorometric)
Glucosylceramidase Activity Assay Kit (Fluorometric)
The product is subject to the following: Abcam Restricted Use Statement
Meso Scale Discovery RPLEX MSE Osteoprotegerin ASY
The Meso Scale Discovery R-PLEX Mouse Osteoprotegerin Assay is a multiplex immunoassay panel that allows simultaneous quantitative measurement of mouse osteoprotegerin (OPG) in serum plasma and cell culture supernatants This assay uses electrochemiluminescence (ECL) detection technology and provides high sensitivity up to 5 logs of dynamic range and low sample volume requirements The assay requires 50 L of sample and can be read on Meso Scale Discovery SECTOR Imagers The assay has a lower limit of detection of 0 04 ng/mL for mouse OPG and a typical assay time of 3 5 hours This assay enables researchers to accurately quantify circulating OPG levels in mouse models
Eurofins Discoverx PathHunter eXpress CALCRL-RAMP2 (AM1) CHO-K1 β-Arrestin GPCR Assay, 2pl Kit. (93-0270E2CP0M)
The PathHunter CALCRL-RAMP2 (AM1) eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. adrenomedullin) based activation of CALCRL GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged CALCRL and EA-tagged β-Arrestin-2, along with untagged modulating protein RAMP2. Activation of CALCRL stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx PathHunter eXpress mEBI2 CHO-K1 β-Arrestin GPCR Assay, 10-Plate Kit. (93-0953E2MCP0L)
The PathHunter mEBI2 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. dihydroxycholesterol) based activation of mEBI2 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged mEBI2 and EA-tagged β-Arrestin-2. Activation of mEBI2 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. Please note that this product expresses the Mouse version of this protein. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
TRIBIOSCIENCE INC Glutathione (GSH) Fluorometric Assay 100 Tests
Tribioscience’s GSH Quantification Fluorometric Assay Kit provides a flexible, accurate, sensitive, and time-saving approach for detecting GSH in a wide variety of samples. In this assay, the non-fluorescent probe binds to the thiol in the sample to produce a fluorescent product which can be measured at 400 nm excitation, 460 nm emission. Features Flexible - Suitable for 96-well and 384-well plate. Accuracy - Fluorescent measurement is proportional to the free thiol content. Sensitive - detection range from 0.3 µM to 20 µM. Time-saving - Just incubate 10 minutes and read out style. Applications Measure free thiol group in a variety samples like cells and tissues.
Eurofins Discoverx PathHunter eXpress OSMRb/IL31RA Dimerization Assay, 2pl Kit. (93-1002E3CP5M)
The PathHunter OSMRb/IL31RA Dimerization eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting receptor-receptor interaction. This kit assesses ligand (e.g. IL-31) induced dimerization of OSMRb/IL31RA receptors. This product uses EFC technology. The cell line included overexpresses OSMRb target protein fused to PK alongside IL31RA target protein fused to EA. Upon ligand-induced dimerization of OSMRb/IL31RA, detectable EFC signal is produced. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx PathHunter Human Ghrelin (GHSR) β-Arrestin-1 Cell-Based Assay Kit (U2OS)
The PathHunter Human Ghrelin (GHSR) β-Arrestin-1 Stable Cell Line Assay (U2OS) contains a stable clonal cell line used to measure GHSR1a (GPCR) activity via recruitment of β-Arrestin-1. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx PathHunter Mouse Insulin Receptor B (INSRb) Functional Kinase Cell-Based Assay Kit (U2OS)
The PathHunter Mouse Insulin Receptor B (INSRb) Stable Cell Line Functional Kinase Assay (U2OS) measures INSRb receptor tyrosine kinase activity via ligand-induced SH2 domain protein recruitment. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx PathHunter Human BCMA Internalization Cell-Based Assay Kit (U2OS)
The PathHunter Human BCMA Stable Cell Line Internalization Assay (U2OS) measures internalization of the BCMA receptor via early-endosome localization. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.