General Cell Based Assays
Eurofins Discoverx PathHunter eXpress IL1RL1/IL1RAP Dimerization Assay, 10pl Kit. (93-1067E3CP5L)
The PathHunter IL1RL1/IL1RAP Dimerization eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting receptor-receptor interaction. This kit assesses ligand (e.g. IL-33) induced dimerization of IL1RL1/IL1RAP receptors. This product uses EFC technology. The cell line included overexpresses IL1RL1 target protein fused to PK alongside IL1RAP target protein fused to EA. Upon ligand-induced dimerization of IL1RL1/IL1RAP, detectable EFC signal is produced. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Meso Scale Discovery R-PLEX Human Reg-3-alpha Assay, Singleplex, 96-well plate, Reg-3-α, LLOD 45 pg/mL, ECL detection, For research use only
R-PLEX Human Reg-3-alpha Assay, Singleplex, 96-well plate, Reg-3-α, LLOD 45 pg/mL, ECL detection, For research use only
American Research Products Inc TFE3 Transcription Factor Activity Assay
TFE3 Transcription Factor Activity Assay
Eurofins Discoverx PathHunter eXpress IL1RL1/IL1RAP Dimerization Assay, 2pl Kit. (93-1067E3CP5M)
The PathHunter IL1RL1/IL1RAP Dimerization eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting receptor-receptor interaction. This kit assesses ligand (e.g. IL-33) induced dimerization of IL1RL1/IL1RAP receptors. This product uses EFC technology. The cell line included overexpresses IL1RL1 target protein fused to PK alongside IL1RAP target protein fused to EA. Upon ligand-induced dimerization of IL1RL1/IL1RAP, detectable EFC signal is produced. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx PathHunter eXpress IL18R1/IL18RAP Dimerization Assay, 10pl Kit. (93-1044E3CP5L)
The PathHunter IL18R1/IL18RAP Dimerization eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting receptor-receptor interaction. This kit assesses ligand (e.g. IL-18) induced dimerization of IL18R1/IL18RAP receptors. This product uses EFC technology. The cell line included overexpresses IL18R1 target protein fused to PK alongside IL18RAP target protein fused to EA. Upon ligand-induced dimerization of IL18R1/IL18RAP, detectable EFC signal is produced. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx PathHunter eXpress GPR30 CHO-K1 β-Arrestin Orphan GPCR Assay, 10-Plate Kit. (93-0373E2ACP2L)
The PathHunter GPR30 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand based activation of GPR30 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged GPR30 and EA-tagged β-Arrestin-2. Activation of GPR30 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. This is an orphan receptor without a known ligand. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx PathHunter Human BMP-4 (BMPR1A/BMPR2) Dimerization Cell-Based Assay Kit (U2OS)
The PathHunter Human BMP-4 (BMPR1A/BMPR2) Stable Cell Line Dimerization Assay (U2OS) measures ligand-induced dimerization of BMPR1A/BMPR2. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
ABclonal Technology HRP-conjugated B-Actin Mouse
This gene encodes one of six different actin proteins Actins are highly conserved proteins that are involved in cell motility structure integrity and intercellular signaling The encoded protein is a major constituent of the contractile apparatus and one of the two nonmuscle cytoskeletal actins that are ubiquitously expressed Mutations in this gene cause Baraitser-Winter syndrome 1 which is characterized by intellectual disability with a distinctive facial appearance in human patients Numerous pseudogenes of this gene have been identified throughout the human genome
Abcam Urokinase type Plasminogen Activator Human Chromogenic Activity Assay Kit - Direct Assay.
Urokinase type Plasminogen Activator Human Chromogenic Activity Assay Kit - Direct Assay.
The product is subject to the following: Abcam Restricted Use Statement
Abcam DNMT3B Assay Kit.
DNMT3B Assay Kit.
The product is subject to the following: Abcam Restricted Use Statement
American Research Products Inc Smad3 Transcription Factor Activity Assay
Smad3 Transcription Factor Activity Assay
Cayman Chemical 7deaza8bromo NAD sodIM 700ug
A derivative of NAD+ and a synthetic intermediate; has been used as an intermediate in the synthesis of cyclic and membrane-permeable diphosphate modulators of TRPM2
Sigma Aldrich Fine Chemicals Biosciences HMG CoA Reductase Assay Ki
The HMG-CoA Reductase Assay Kit is an important tool for the basic research of cholesterol and other relelated metabolic pathways.
Eurofins Discoverx PathHunter eXpress OPRM1 U2OS β-Arrestin GPCR Assay, 2-Plate Kit. (93-0213E3CP0M)
The PathHunter OPRM1 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. met 5-enkephalin) based activation of OPRM1 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged OPRM1 and EA-tagged β-Arrestin-2. Activation of OPRM1 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx PathHunter Human Activin B (ACVR1C/ACVR2B) Dimerization Cell-Based Assay Kit (U2OS)
The PathHunter Human Activin B (ACVR1C/ACVR2B) Stable Cell Line Dimerization Assay (U2OS) measures ligand-induced dimerization of ACVR1C/ACVR2B. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.