General Cell Based Assays
Revvity Health Sciences Inc HTRF Human Total IκKβ Detection Kit, 10,000 Assay Points
HTRF Human Total IκKβ Detection Kit, 10,000 Assay Points
Eurofins Discoverx PathHunter Human Mer Functional Kinase Cell-Based Assay Kit (U2OS)
The PathHunter Human Mer Stable Cell Line Functional Kinase Assay (U2OS) measures activation through receptor dimerization leading to SH2-binding protein recruitment. This complete kit includes cell line vials and all required reagents for cell culture, maintenance and for running the assay.
Eurofins Discoverx PathHunter Human GPR176 β-Arrestin Cell-Based Assay Kit (CHO-K1)
The PathHunter Human GPR176 β-Arrestin Stable Cell Line Assay (CHO-K1) contains a stable clonal cell line used to measure GPR176 (GPCR) activity via recruitment of β-Arrestin2. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx PathHunter eXpress F2RL1 Activated GPCR Internalization Assay, 10pl Kit. (93-0747E3CP5L)
The PathHunter F2RL1 Activated GPCR internalization eXpress kit provides an easy to-use cell based assay to study drug candidates (small molecules or biologics) affecting GPCR activation and internalization. This kit uses EFC technology to measure ligand-induced internalization of F2RL1 via detection of localization to the early endosome. The included cell line overexpresses EA-tagged β-Arrestin-2 as well as a ProLink-tagged early endosome protein and untagged F2RL1. Upon ligand-induced receptor activation, β-Arrestin-2 is recruited to the activated GPCR and the resulting F2RL1-arrestin complex is internalized to the early endosome, leading to production of EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx PathHunter Human TGFBR1/ACVR2 Dimerization Cell-Based Assay Kit (U2OS)
The PathHunter Human TGFBR1/ACVR2 Dimerization Stable Cell Line Assay (U2OS) measures ligand-induced dimerization of TGFBR1A/ACVR2A. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx PathHunter Human GPR52 β-Arrestin Cell-Based Assay Kit (CHO-K1)
The PathHunter Human GPR52 β-Arrestin Stable Cell Line Assay (CHO-K1) contains a stable clonal cell line used to measure GPR52 (GPCR) activity via recruitment of β-Arrestin2. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx PathHunter Human PDGFRb Functional Kinase Cell-Based Assay Kit (U2OS)
The PathHunter Human PDGFRb Stable Cell Line Functional Kinase Assay (U2OS) measures PDGFRb receptor tyrosine kinase activity via ligand-induced SH2 domain protein recruitment. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx PathHunter Human MRGPRX2 β-Arrestin Cell-Based Assay Kit (CHO-K1)
The PathHunter Human MRGPRX2 β-Arrestin Stable Cell Line Assay (CHO-K1) contains a stable clonal cell line used to measure MRGPRX2 (GPCR) activity via recruitment of β-Arrestin2. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx InCELL Hunter eXpress CLK2 Kinase Binding Assay, 10pl Kit. (96-0057E15CP0L)
The InCELL Hunter eXpress CLK2 Kinase Binding Assay provides an easy-to-use cell based assay to study small molecule drug candidates that engage with kinases. This kit assesses compound-engagement-based stabilization of CLK2 via detection of CLK2 levels. This product uses EFC technology. The cell line included overexpresses CLK2 target protein fused to ProLabel. In the absence of compound that binds and stabilizes the target, this protein is degraded and no EFC signal is produced. When compound engages and stabilizes the target, EA contained in the detection reagent produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx AssayComplete Cell Plating 14 Reagent, 100. (93-0563R14A)
AssayComplete Cell Plating 14 Reagent is an optimized cell plating reagent for use in plating of Eurofins DiscoverX cell lines for assays. This reagent was optimized for maximal cell health and ligand responsiveness during assays while eliminating hormones and growth components which may lead to increased basal activity. This product is provided as a bottle of 100 mL. Please refer to cell line specific datasheet to determine the recommended cell plating reagent. For detailed product information, User manual and datasheet, visit www.discoverx.com/reagents.
Abcam GSSG Probe.
GSSG Probe.
The product is subject to the following: Abcam Restricted Use Statement
Cayman Chemical MPO asy Buffer1X 1ea
A - and K1-opioid receptor antagonist (Kis 0.3 and 0.2 nM respectively) selective for - and K1-opioid receptors over the -opioid receptor (Ki 12.8 nM) reversibly inhibits electricity-induced twitches of isolated guinea pig ileal longitudinal muscle strips (IC50 48 nM) indicating opioid agonist activity inhibits endomorphin 1-induced conditioned place preference in mice at 0.3 UG/animal i.c.v. prevents decreases in urine output induced by fentanyl D-propoxyphene buprenorphine profadol or bromadoline in water-loaded rats at 40 mg/kg reduces hemokinin 1-induced increases in the latency to withdrawal in the tail-flick test in mice
Abcam colorimetric/fluorometric ..
colorimetric/fluorometric ..
The product is subject to the following: Abcam Restricted Use Statement
Eurofins Discoverx PathHunter Human P2RY12 Total GPCR Internalization Cell-Based Assay Kit (U2OS)
The PathHunter Human P2RY12 Stable Cell Line Total GPCR Internalization Assay (U2OS) contains a stable clonal cell line used to measure P2RY12 (GPCR) internalization via early-endosome localization. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx PathHunter Human EphA5 Functional Kinase Cell-Based Assay Kit (U2OS)
The PathHunter Human EphA5 Stable Cell Line Functional Kinase Assay (U2OS) measures EphA5 receptor tyrosine kinase activity via ligand-induced SH2 domain protein recruitment. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.