Protease Inhibitors and Phosphatase Inhibitors
MilliporeSigma™ Calbiochem™ Diethyl Pyrocarbonate
Inhibits ryanodine binding to ryanodine/Ca2+ receptor channel in skeletal muscle in a dose- and time-dependent manner and increases the Ca2+ permeability of SR vesicles.
MilliporeSigma™ Calbiochem™ Cathepsin D Substrate I
Useful as a substrate for the determination of cathepsin D activity.
MilliporeSigma™ Calbiochem™ Amyloid Precursor Protein β-Secretase Inhibitor
The Amyloid Precursor Protein β-Secretase Inhibitor controls the biological activity of Amyloid Precursor Protein β-Secretase. This small molecule/inhibitor is primarily used for Neuroscience applications.
MilliporeSigma™ Calbiochem™ Lactate Dehydrogenase A Inhibitor, FX11
Lactate Dehydrogenase A Inhibitor, FX11, CAS 213971-34-7, is a cell permeable, selective, reversible, NADH competitive inhibitor of lactate dehhydrogenase A (LDHA; Ki = 8μM for human liver LDHA).
MilliporeSigma™ Calbiochem™ GR 127935 Hydrochloride
A selective 5-HT1B/1D receptor antagon
MilliporeSigma™ Calbiochem™ MK-2 Inhibitor III
The MK-2 Inhibitor III, also referenced under CAS 1186648-22-5, controls the biological activity of MK-2. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ Hh/Gli Antagonist, GANT58
The Hh/Gli Antagonist, GANT58, also referenced under CAS 64048-12-0, controls the biological activity of Hh/Gli. This small molecule/inhibitor is primarily used for Cell Signaling applications.
MilliporeSigma™ Calbiochem™ IκB Kinase Inhibitor Peptide, Cell-Permeable
The IκB Kinase Inhibitor Peptide, Cell-Permeable controls the biological activity of IκB Kinase. This small molecule/inhibitor is primarily used for Inflammation/Immunology applications.
MilliporeSigma™ Calbiochem™ p53 Activator VII, STIMA-1
The p53 Activator VII, STIMA-1, also referenced under CAS 91634-12-7, modulates the biological activity of p53. This small molecule/inhibitor is primarily used for Activators/Inducers applications.
MilliporeSigma™ Calbiochem™ HBDDE
A cell-permeable protein kinase C (PKC) inhibitor that selectively inhibits PKCα and PKCγ over PKCδ, βI, and βII isozymes in in vitro assays.
MilliporeSigma™ Calbiochem™ Calpastatin Peptide, Negative Control
A scrambled peptide with an identical amino acid composition to that of Calpastatin Peptide. Useful as a negative control for Calpastatin Peptide.
MilliporeSigma™ Calbiochem™ Pifithrin-μ
Pifithrin-μ, CAS 64984-31-2, is a cell-permeable inhibitor of p53 interaction with Bcl-xL and Bcl-2. Inhibits p53 translocation to mitochondria without affecting the transactivation function of p53.
MilliporeSigma™ Calbiochem™ p38 MAP Kinase Inhibitor X, BIRB 796
The p38 MAP Kinase Inhibitor X, BIRB 796, also referenced under CAS 285983-48-4, controls the biological activity of p38 MAP Kinase. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ InSolution™ EZH2 Inhibitor, DZNep
A 25 mM (1 mg/98 μL) sterile-filtered solution of Histone Methyltransferase EZH2 Inhibitor, DZNep in H2O.
MilliporeSigma™ Calbiochem™ Citalopram Hydrobromide
A potent uptake inhibitor highly selective for 5-HT transporter without effect on noradrenalin or dopamine uptake (IC50