Protease Inhibitors and Phosphatase Inhibitors
MilliporeSigma™ Calbiochem™ Parthenolide, Tanacetum parthenium
A cell-permeable sesquiterpene lactone with anti-inflammatory, antisecretory, and spasmolytic properties.
MilliporeSigma™ Calbiochem™ Wnt Antagonist III, Box5
The Wnt Antagonist III, Box5 controls the biological activity of Wnt. This small molecule/inhibitor is primarily used for Cancer applications.
MilliporeSigma™ Calbiochem™ FATP2 Inhibitor, CB-2
A cell permeable thioxothiazolindine compound that reversibly inhibits FATP2-mediated long chain fatty acid uptake in Caco-2 and HepG2, but not non-FATP2-expressing 3T3-L1 adipocytes, cultures (IC50
MilliporeSigma™ Calbiochem™ TSPO Agonist, Ro5-4864
A 4'-chloro derivative of diazepam that lacks affinity for GABA-A receptors, but can serve as a ligand for the peripheral benzodiazepine receptor.
MilliporeSigma™ Calbiochem™ HIF-PHD Inhibitor II, JNJ-42041935
The HIF-PHD Inhibitor II, JNJ-42041935 controls the biological activity of HIF-PHD. This small molecule/inhibitor is primarily used for Cell Structure applications.
MilliporeSigma™ Calbiochem™ MDM2 Antagonist, Nutlin-3, Racemic
The MDM2 Antagonist, Nutlin-3, Racemic, also referenced under CAS 548472-68-0, controls the biological activity of MDM2. This small molecule/inhibitor is primarily used for Cancer applications.
MilliporeSigma™ Calbiochem™ Aphidicolin
Aphidicolin, CAS 38966-21-1, is a cell-permeable antibiotic that acts as a cell synchronization agent. Blocks the cell cycle at early S-phase.
MilliporeSigma™ Calbiochem™ SANT-1
A potent, cell-permeable antagonist of the Shh signaling pathway by binding directly to Smoothened, a distant relative of G protein-coupled receptors.
MilliporeSigma™ Calbiochem™ PKA Inhibitor 5-24
The PKA Inhibitor 5-24, also referenced under CAS 99534-03-9, controls the biological activity of PKA.
MilliporeSigma™ Calbiochem™ SKP2 E3 Ligase Inhibitor IV
A cell-permeable inhibitor of SKP2-dependent p27Kip1 ubiquitination. Selectively induces the accumulation SCFSKP2 substrates in multiple myeloma RPMI 8226 cells.
MilliporeSigma™ Calbiochem™ BMX/BTK Inhibitor II, QL47
A cell-permeable, highly potent, selective, irreversible inhibitor of BTK (IC50 = 6.6 nM).
MilliporeSigma™ Calbiochem™ Adenosine 3',5'-cyclic Monophosphorothioate, 8-Bromo-, Rp-Isomer, Sodium Salt
A potent, cell-permeable, and reversible metabolically-stable cAMP antagonist that inhibits cAMP-dependent protein kinase and shows preference for PKA type I.
MilliporeSigma™ Calbiochem™ AMPK Activator V, Ampkinone
The AMPK Activator V, Ampkinone modulates the biological activity of AMPK. This small molecule/inhibitor is primarily used for Biochemicals applications.
MilliporeSigma™ Calbiochem™ Colcemid
Cell synchronization agent.
MilliporeSigma™ Calbiochem™ HDL Receptor SR-BI Inhibitor, BLT-1
The HDL Receptor SR-BI Inhibitor, BLT-1, also referenced under CAS 321673-30-7, controls the biological activity of HDL Receptor SR-B. This small molecule/inhibitor is primarily used for Phosphorylation and Dephosphorylation applications.