Protease Inhibitors and Phosphatase Inhibitors
MilliporeSigma™ Calbiochem™ AMPA Agonist, CMPA
The AMPA Agonist, CMPA controls the biological activity of AMPA. This small molecule/inhibitor is primarily used for Biochemicals applications.
MilliporeSigma™ Calbiochem™ Hydroxyurea
Anti-neoplastic agent that blocks DNA replication by inhibiting ribonucleotide reductase.
MilliporeSigma™ Calbiochem™ NS309
A potent activator of Ca2+ -activated K+ channels of SK and IK types, but not BK type channels. It is at least 1000 times more potent than 1-EBIO.
MilliporeSigma™ Calbiochem™ GSK-3β Inhibitor I
The GSK-3β Inhibitor I, also referenced under CAS 327036-89-5, controls the biological activity of GSK-3β. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ GSK-3 Inhibitor X
The GSK-3 Inhibitor X, also referenced under CAS 740841-15-0, controls the biological activity of GSK-3. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ HSP90 Inhibitor, CCT018159
The HSP90 Inhibitor, CCT018159, also referenced under CAS 171009-07-7, controls the biological activity of HSP90.
MilliporeSigma™ Calbiochem™ GPR119 Agonist, AS1269574
The GPR119 Agonist, AS1269574, also referenced under CAS 330981-72-1, controls the biological activity of GPR119. This small molecule/inhibitor is primarily used for Biochemicals applications.
MilliporeSigma™ Calbiochem™ IKK Inhibitor III, BMS-345541
IKK Inhibitor III, BMS-345541, CAS 445430-58-0, is a cell-permeable, potent, selective, and allosteric site-binding inhibitor of IKK-2 (IC50 = ≈300 nM).
MilliporeSigma™ Calbiochem™ SHIP1 Inhibitor, 3AC
The SHIP1 Inhibitor, 3AC controls the biological activity of SHIP1. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ Nef Hck Activation Inhibitor, B9
A cell-permeable diphenylpyrazolo compound that disrupts HIV accessary protein Nef dimerization (IC50 = 3μM in HEK293T cells) and prevents Nef-mediated Src family kinase Hck activation (IC50 )
MilliporeSigma™ Calbiochem™ Glucagon Receptor Antagonist II
The Glucagon Receptor Antagonist II, also referenced under CAS 191034-25-0, controls the biological activity of Glucagon Receptor.
MilliporeSigma™ Calbiochem™ 5,7-Dichlorokynurenic Acid, Sodium Salt
A very potent, water-soluble antagonist of the NMDA receptors complex acting at the strychnine-insensitive glycine binding site (Ki = 79 nM
MilliporeSigma™ Calbiochem™ Paclitaxel, Semi-Synthetic
A semi-synthetic form of Paclitaxel having no contamination by natural taxanes. Also has reduced levels of epimerization products as contaminants.
MilliporeSigma™ Calbiochem™ Acetyl-Pepstatin
An aspartyl protease inhibitor that acts as an effective inhibitor of HIV-1 proteinase (Ki = 20nM at pH 4.7) and HIV-2 proteinase (Ki = 5nM at pH 4.7).
MilliporeSigma™ Calbiochem™ Spermidine, Trihydrochloride
Polyamine that plays an important role in the regulation of cellular proliferation and differentiation.