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GFR alpha -like (GDNF receptor-alpha-like) is a distant member of the GDNFR family of proteins Mature human GFR alpha-like is a 376 amino acid (aa) type I transmembrane protein It contains a 333 aa extracellular domain a 20 aa transmembrane domain and a 23 aa cytoplasmic domain GFRAL is a brainstem-restricted receptor for GDF15 which regulates food intake energy expenditure and body weight in response to metabolic and toxin-induced stresses
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Protein kinase C (PKC) is a family of serine- and threonine-specific kinases activated by calcium and diacylglycerol PKC family members phosphorylate various protein targets and are involved in multiple cellular signaling pathways They also serve as receptors for phorbol esters tumor-promoting compounds Each PKC member has a distinct expression profile and role in cells The protein encoded by this gene is a PKC family member involved in B cell activation apoptosis endothelial cell proliferation and intestinal sugar absorption Studies in mice suggest it may also regulate neuronal functions and influence fear-induced behavior after stress Alternative splicing generates distinct isoforms of this gene
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
GFR alpha -like (GDNF receptor-alpha-like) is a distant member of the GDNFR family of proteins Mature human GFR alpha-like is a 376 amino acid (aa) type I transmembrane protein It contains a 333 aa extracellular domain a 20 aa transmembrane domain and a 23 aa cytoplasmic domain GFRAL is a brainstem-restricted receptor for GDF15 which regulates food intake energy expenditure and body weight in response to metabolic and toxin-induced stresses
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
Recombinant rat Collagen alpha-3(IV) chain fragment (tumstatin) expressed in HEK293 cells and fused to an N-terminal human Fc tag. Supplied as a filtered PBS solution, this partial construct (G1426-H1670) is suitable for ELISA, antibody generation, and functional assays.
Expressed in HEK293 cells with N-terminal human Fc tag.
Partial COL4A3 fragment corresponding to residues G1426-H1670.
Molecular weight approximately 59 kDa.
Purity >90% by reducing SDS-PAGE.
Supplied as 0.22 μm filtered PBS solution, pH 7.4.
Endotoxin <1 EU/μg (LAL method).
Store at -80°C; shipped on dry ice.
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More