Drugs of Abuse Clinical Controls and Calibrators
Cayman Chemical Sitagliptin Positive Control Inhibitor, 500 nmol
Sitagliptin Positive Control Inhibitor, 500 nmol
Cayman Chemical L3MBTL1 PosItIve CNTRL 160nmol
A covalent inhibitor of PME-1 (IC50 0.6 UM) reduces the levels of methylated PP2A in HEK293T cells stably overexpressing PME-1 at 20 UM. AMZ30 inhibits t-BHP-induced decreases in U87MG and U-251MG cells at 210 UM
Cerilliant Corporation Clonidine, 4205-90-7, MFCD00055059, 1mg/mL
Empirical Formula (Hill Notation): C9H9Cl2N3, Molecular Weight: 230.09, 1.0 mg/mL in Methanol. Clonidine is a pharmaceutical drug used to treat a wide variety of conditions including hypertension, ADHD, insomnia, chemical withdrawal, and anxiety. Clonidine is often prescribed in combination with other drugs, depending on the clinical condition. This analytical reference standard is suitable for use as starting material in calibrators or controls for a variety of LC/MS or GC/MS applications from forensic analysis and clinical toxicology to pharmaceutical research.
Cayman Chemical ICBP112 PosItIve CNTRL 120nmol
An activator of the STING pathway induces secretion of IFN-B in human PBMCs (EC50 130 nM) increases serum levels of Ifn-B Il-6 Tnf and Cxcl1 in wild-type but not Sting-/- mice at 2.5 mg/kg inhibits the cytopathic effect of HCoV-229E in infected MRC-5 cells (EC50 3 nM) decreases the level of SARS-CoV-2 RNA in primary human bronchial airway epithelial cells in an air-liquid interface assay decreases tumor volume and increases survival in a CT26 murine colorectal cancer model at 3 mg/kg this compound is expected to exist in one or both tautomeric forms