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1-Palmitoyl-sn-glycero-3-phosphocholine-d49 is the deuterium-labeled isotopologue of 1-palmitoyl-sn-glycero-3-phosphocholine (16:0 Lyso PC). Supplied as a solid, it is used as an analytical reference and internal standard in lipidomics and mass spectrometry workflows to enable accurate quantitation of lysophosphatidylcholine species.
Isotopically labeled with 49 deuterium atoms (d49).
Chemical formula C24HD49NO7P.
Molecular weight 544.93.
CAS number 2315262-40-7.
Supplied as a solid in small pack sizes, suitable for analytical use.
Intended for use as an internal standard in LC-MS/MS and lipid analysis.
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Lyso-PAF C-16 can be formed by either the action of PAF-AH on PAF C-16,{2626} or by the action of a CoA-independent transacylase on 1-O-hexadecyl-2-acyl-glycerophosphocholine.{240,2098} Lyso-PAF C-16 is a substrate for either PAF C-16 formation by the remodeling pathway{939} or selective acylation with arachidonic acid by a CoA-independent transacylase.{2101}
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An ionizable cationic lipid; has been used in the formation of LNPs; LNPs containing DLin-MC2-DMA and encapsulating siRNA targeting mRNA encoding FVII reduce hepatic levels of FVII in mice (ED50 = 0.6 mg/kg)
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DMG-PEG2000-NHS is a polyethylene glycol (PEG) derivative functionalized with an N-hydroxysuccinimide (NHS) ester The reactive NHS ester readily forms stable amide linkages upon interaction with primary amine (-NH ) groups facilitating covalent attachment to peptides proteins or amino-functionalized small molecules Due to these conjugation properties DMG-PEG2000-NHS is commonly employed in biomedical research for constructing drug delivery platforms such as lipid nanoparticles (LNPs) or liposomes particularly for siRNA delivery systems
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DMG-PEG2000-Biotin is a synthetic amphiphilic molecule composed of dimyristoyl glycerol (DMG) polyethylene glycol (PEG2000) and biotin functionalities It is commonly employed in biomedical research for surface modification of lipid-based delivery platforms such as lipid nanoparticles (LNPs) and liposomes The PEG moiety enhances colloidal stability prolongs circulation time and reduces rapid clearance in vivo The biotin termination facilitates conjugation to streptavidin-tagged biomolecules exploiting the highly specific biotin-streptavidin interaction Thus DMG-PEG2000-Biotin is valuable for drug-delivery optimization targeted therapeutic approaches and in vitro diagnostic assay development
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A triacylglycerol; has been found in Kpangnana, Chinese tallow, and cocoa butters; increases the phagocytic function of reticulo-endothelial cells in mice at 5 and 10 mg per animal
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