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Molecular Formula C24H46O9PNa, Purity >99% LPG; may contain up to 10% of the 2-LPG isomer, Formula Weight 532.580, Storage Temperature -20°C, 1-oleoyl-2-hydroxy-sn-glycero-3-phospho-(1'-rac-glycerol) (sodium salt)
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18:1 PEG2000 PE ammonium salt is a PEGylated phosphoethanolamine that attaches a methoxy-PEG2000 chain to phosphatidylethanolamine, enabling incorporation of a hydrophilic PEG surface into lipid bilayers and nanoparticle formulations. It is used in liposome and nanoparticle preparation, membrane model studies, and surface modification to impart steric stabilization and reduce aggregation.
Provides steric stabilization to lipid bilayers and nanoparticles.
Increases hydrophilicity and reduces aggregation of lipid assemblies.
Suitable for liposome and nanoparticle formulation and membrane model systems.
Reported high purity (>99%), suitable for research applications.
Powder form; hygroscopic and recommended storage at -20 °C.
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DLin-KC2-DMA is an ionizable cationic lipid (pKa≈6) that is virtually non-toxic to antigen presenting cells (APCs). It produces significant siRNA-mediated gene silencing of GAPDH when bound to lipid nanoparticles (LNP). DLin-KC2-DMA can be used in siRNA delivery studies.
Ionizable cationic lipid (pKa≈6).
Virtually non-toxic to antigen presenting cells (APCs).
Produces significant siRNA-mediated gene silencing of GAPDH when bound to lipid nanoparticles (LNP).
Can be used in siRNA delivery studies.
High uptake into macrophages and dendritic cells.
Efficiently promotes release of encapsulated siRNA into the cytosol following uptake via the endocytotic pathway.
Displays almost no toxicity in primary APCs.
Effective in silencing target genes in APCs in vivo (5 mg/kg; i.v.; single).
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A triacylglycerol; been used to characterize the functionality of R. oryzae lipase for regiodistribution analysis of fats containing medium- and short-chain fatty acids
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