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OSM-SMI-10B is a derivative of OSM-SMI-10 that significantly reduces OSM-induced STAT3 phosphorylation in cancer cells upon co-incubation with Oncostatin M (OSM). This compound targets p-STAT3 and is involved in JAK/STAT Signaling and Stem Cell/Wnt pathways.
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OSM-SMI-10B is a derivative of OSM-SMI-10 that significantly reduces Oncostatin M (OSM)-induced STAT3 phosphorylation in cancer cells upon co-incubation with OSM.
Targets p-STAT3
Molecular weight: 378.33
Formula: C21H14O7
Appearance: Solid
Color: Light yellow to yellow
Storage: Powder at -20°C for 3 years or 4°C for 2 years; in solvent at -80°C for 6 months or -20°C for 1 month
Solubility in vitro: DMSO: 250 mg/mL (660.80 mM)
Solubility in vivo: ≥ 6.25 mg/mL (16.52 mM)
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