Osmometer Controls
Medchemexpress LLC OSM-S-106 | 2650846-59-4 | 99.3% | 306.36 | 5 MG
OSM-S-106 is a pro-inhibitor that inhibits PfAsnRS via enzyme-mediated production of an Asn-OSM-S-106 adduct. It inhibits protein translation and activates the amino acid starvation response. This product exhibits selective activity against Plasmodium blood and liver stages and has low intrinsic clearance by human microsomes.
- Inhibits protein translation
- Activates the amino acid starvation response
- Selective activity against Plasmodium blood and liver stages
- Low intrinsic clearance by human microsomes
Medchemexpress LLC OSM-S-106 | 2650846-59-4 | 99.3% | 306.36 | 50 MG
OSM-S-106 is a pro-inhibitor that works by inhibiting PfAsnRS through an enzyme-mediated adduct formation. It effectively blocks protein translation and triggers an amino acid starvation response. The compound demonstrates selective activity against both Plasmodium blood and liver stages, and exhibits low intrinsic clearance by human microsomes.
- Inhibits PfAsnRS via an enzyme-mediated adduct.
- Blocks protein translation.
- Activates amino acid starvation response.
- Selectively active against Plasmodium blood and liver stages.
- Low intrinsic clearance by human microsomes.
Medchemexpress LLC Osm-S-106 | 2650846-59-4 | 99.3% | 306.36 g·mol-1 | C12H10N4O2S2 | 10 MG
OSM-S-106 is a small-molecule pro-inhibitor of Plasmodium falciparum asparagine tRNA synthetase (PfAsnRS). It inhibits protein translation by forming an enzyme-mediated Asn adduct, activates the amino acid starvation response, and shows selective activity against Plasmodium blood and liver stages. Supplied as a high-purity research reagent for parasitology and antimalarial mechanism-of-action studies.
- High purity (99.34%) suitable for research applications.
- Well-characterized chemical identity: C12H10N4O2S2, MW 306.36 g·mol-1.
- Mechanism: reaction-hijacking pro-inhibitor that targets PfAsnRS.
- Selective activity against Plasmodium blood and liver stages.
- Provided with product datasheet and analytical information for quality control.
- Store and handle according to supplier datasheet recommendations.