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Filtered Search Results
Medchemexpress LLC Grazoprevir potassium salt | 1206524-86-8 | C38H49KN6O9S | 1 ML
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Grazoprevir potassium salt is a selective inhibitor of Hepatitis C virus NS3/4a protease with broad activity across various genotypes and resistant variants. It also inhibits SARS-CoV-2 3CLpro activity. This product is for research use only.
- Selective inhibitor of Hepatitis C virus NS3/4a protease
- Broad activity across various genotypes and resistant variants
- Inhibits SARS-CoV-2 3CLpro activity
- Potent against HCV replication mutants NS5A (Y93H), NS5B nucleosides (S282T), and NS5B (C316Y)
- Demonstrates in vivo efficacy against chronic-HCV-infected chimpanzees
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Jorgensen Labs SHEATHER'S SUGAR FLOTATN 1GAL
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Sheather’s Sugar Flotation 1gallon bottle
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Medchemexpress LLC Cyclophilin inhibitor 1 | 1509904-96-4 | 99.5% | 593.67 | 25 MG
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Cyclophilin inhibitor 1 is a potent and orally bioavailable cyclophilin A inhibitor, with a Kd of 5 nM, and shows effective anti-HCV activity, with an EC50 of 98 nM for HCV 2a.
- Potent and orally bioavailable cyclophilin A inhibitor.
- Kd of 5 nM for cyclophilin A.
- Effective anti-HCV activity, with an EC50 of 98 nM for HCV 2a.
- Appearance: Solid, white to off-white.
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Medchemexpress LLC K-Ras(G12C) inhibitor 12 | 1469337-95-8 | 99.6% | 449.67 | 5 MG
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K-Ras(G12C) inhibitor 12 is an irreversible inhibitor of K-Ras(G12C). It can alter the nucleotide-binding preference of K-Ras and block its interaction with effector proteins. K-Ras(G12C) inhibitor 12 can reduce cell viability and induce apoptosis in lung cancer cell lines with G12C mutations and has anti-tumor activity. It is for research use only.
- Irreversible inhibitor of K-Ras(G12C)
- Reduces cell viability and induces apoptosis in lung cancer cell lines with G12C mutations
- Has anti-tumor activity
- Appears as a solid, white to light yellow
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Medchemexpress LLC Human PD-L1 inhibitor II | 2135542-85-5 | 98.3% | 2219.45 | 10 MG
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Human PD-L1 inhibitor II is a potent PD-L1 inhibitor with anti-cancer activity. It appears as a white to off-white solid.
- Potent PD-L1 inhibitor with anti-cancer activity
- White to off-white solid appearance
- Soluble in H2O at 25 mg/mL (11.26 mM) with ultrasonic assistance
- Ships at room temperature in continental US
- Powder storage: -80°C for 2 years, -20°C for 1 year (sealed, away from moisture and light, under nitrogen)
- In solvent storage: -80°C for 6 months, -20°C for 1 month (sealed, away from moisture and light, under nitrogen)
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Medchemexpress LLC Human PD-L1 inhibitor I | 2135542-86-6 | 98.9% | 2350.58 | 5 MG
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The product is a peptide ligand that interacts with a protein involved in immune checkpoints. This peptide may disrupt the binding of two key proteins, with a dissociation constant (KD) of 3.39 μM. It is intended for research purposes only.
- Biological activity: It functions as a ligand for the protein, demonstrating a binding affinity with a KD of 3.39 μM.
- Mechanism of action: This peptide is thought to interfere with the interaction between two specific human proteins.
- Physical characteristics: It appears as a solid, white to off-white in color.
- Storage conditions: Sealed storage, protected from moisture and light, under nitrogen.
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Medchemexpress LLC Lyn peptide inhibitor | 222018-18-0 | 99.4% | 2370.88 | 10 MG
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Lyn peptide inhibitor is a potent and cell-permeable inhibitor of the Lyn-coupled IL-5 receptor signaling pathway. It blocks Lyn activation and inhibits the binding of Lyn tyrosine kinase to the βc subunit of IL-3/GM-CSF/IL-5 receptors. This inhibitor is useful for the study of asthma, allergic, and other eosinophilic disorders.
- Potent and cell-permeable inhibitor
- Blocks Lyn activation
- Inhibits binding of Lyn tyrosine kinase to βc subunit of IL-3/GM-CSF/IL-5 receptors
- White to off-white solid appearance
- Soluble in DMSO: 5 mg/mL (2.11 mM; requires ultrasonic)
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Medchemexpress LLC Human PD-L1 inhibitor IV | 2135542-83-3 | 99.9% | 1856.90 | 5 MG
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Human PD-L1 inhibitor IV is a polypeptide that acts as a competitive inhibitor of human PD-1 protein. It has a Kd value of 1.38 μM and is designed to inhibit the interaction between hPD-1 and hPD-L1. This product is for research use only.
- Polypeptide composition
- Competitive human PD-1 protein inhibitor
- Kd value of 1.38 μM
- Inhibits hPD-1/hPD-L1 interaction
- For research use only
- White to off-white solid
- Requires sealed storage, away from moisture and light, under nitrogen
- Soluble in DMSO at 50 mg/mL
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Medchemexpress LLC ω-hydroxy-DEET | 72236-22-7 | MFCD00871280 | 98.6% | 207.27 g/mol | C12H17NO2 | 5 MG
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ω-Hydroxy-DEET (N,N-diethyl-3-(hydroxymethyl)benzamide) is a research-grade small molecule and a major metabolite of the insect repellent DEET, provided as a high-purity reference standard for biochemical and pharmacological studies. It is identified by CAS 72236-22-7, has formula C12H17NO2 and a molecular weight of 207.27 g/mol.
- High purity (98.6%), suitable for analytical and assay work.
- Soluble in DMSO at high concentration (≥100 mg/mL).
- Liquid appearance, colorless to light yellow, with documented density.
- Stable when stored protected from light; recommended cold storage for solutions.
- Intended for research and analytical applications as a metabolite standard.
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Medchemexpress LLC Lyn peptide inhibitor | 222018-18-0 | 99.35% | 2370.88 | 1 MG
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Lyn peptide inhibitor is a potent and cell-permeable inhibitor of the Lyn-coupled IL-5 receptor signaling pathway, while keeping other signals intact. It blocks Lyn activation and inhibits the binding of Lyn tyrosine kinase to the βc subunit of IL-3/GM-CSF/IL-5 receptors. It can be used for the study of asthma, allergic, and other eosinophilic disorders.
- Potent and cell-permeable inhibitor
- Blocks Lyn activation
- Inhibits binding to βc subunit of IL-3/GM-CSF/IL-5 receptors
- Useful for studying asthma, allergic, and eosinophilic disorders
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Aqua Solutions Hydrogen Peroxide 5% w/w Solution, Lab Grade (1L)
Hydrogen Peroxide 5% w/w Solution, Lab Grade (1L)
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Medchemexpress LLC Phosphatase Inhibitor Cocktail III (100x in DMSO) | 1 ML
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Phosphatase Inhibitor Cocktail III (100x in DMSO) is a blend of three phosphatase inhibitors designed to effectively inhibit serine/threonine phosphatases and alkaline phosphatases. This cocktail helps maintain the phosphorylation status of proteins by preventing degradation, which is often enhanced when cells are studied in vitro.
- Effectively inhibits serine/threonine phosphatases
- Effectively inhibits alkaline phosphatases
- Maintains the phosphorylation status of proteins
- Prevents protein degradation
- Suitable for Western Blot analysis
- Suitable for IP
- Suitable for Co-IP
- Suitable for pull-down assays
- Suitable for immunofluorescence (IF)
- Suitable for immunohistochemistry (IHC)
- Suitable for kinase assays
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LaMarKa Chemical Company Sodium Hydroxide 17%W/W / Sodium Carbonate 7%W/W, 250ml
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Sodium Hydroxide 17%W/W / Sodium Carbonate 7%W/W, 250ml Plastic Bottle
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LaMarKa Chemical Company Hydrochloric Acid6N ( 1:1 V/V ), 0.5l
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Hydrochloric Acid6N ( 1:1 V/V ), 0.5l Plastic Bottle
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Medchemexpress LLC Th34 10 Mm 1 Ml In Dmso Soluti | HY-111818-10 MM
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Th34 10 Mm 1 Ml In Dmso Soluti
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