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Filtered Search Results
Selleck Chemical LLC LDN-212854
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LDN-212854 (BMP Inhibitor III) is a potent and selective BMP receptor inhibitor with IC50 of 1 3 nM for ALK2 about 2- 66- 1641- and 7135-fold selectivity over ALK1 ALK3 ALK4 and ALK5 respectively
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Medchemexpress LLC 4-(4-(6-methoxynaphthalen-2-yl)-2-(4-(methylsulfinyl)phenyl)-1H-imidazol-5-yl)pyridine | 948557-43-5 | MFCD14585804 | >=95.0% | 439.53 g/mol | C26H21N3O2S | 5 MG
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Tie2 kinase inhibitor 1 is a small-molecule, selective inhibitor of the Tie2 receptor tyrosine kinase with reported anti-cancer activity. It has a reported biochemical IC50 of 250 nM and is supplied for research use.
- Selective Tie2 kinase inhibition with an IC50 of 250 nM.
- Reported anti-cancer activity in preclinical studies.
- Molecular formula C26H21N3O2S and molecular weight 439.53 g/mol.
- CAS number 948557-43-5 for unambiguous identification.
- Purity ≥95% as reported by suppliers.
- Available in small research quantities (example 5 mg).
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LaMarKa Chemical Company Hydrochloric Acid 1.0N Phenolphthalein Endpoint, 1l
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Hydrochloric Acid 1.0N Phenolphthalein Endpoint, 1l Plastic Bottle
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LaMarKa Chemical Company Hydrolyzable Chloride Reactant 1 gal
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Reagent 35 Total Hydrolyzable Chloride Reactant-Bottle Gallon Amber Glass
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Medchemexpress LLC DTPA-tetra (t-Bu ester) | 174267-71-1 | 99.0% | C30H55N3O10 | 100 MG
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DTPA-tetra (t-Bu ester) is identified as a bifunctional chelator (BFC) and a macrocyclic DPTA derivative. This compound is utilized in research for tumor pre-targeting. Its chemical structure allows for the conjugation of peptides and radionuclides.
- Bifunctional chelator (BFC)
- Macrocyclic DPTA derivative
- Used for tumor pre-targeting
- Can be used for conjugation of peptides
- Can be used for conjugation of radionuclides
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Medchemexpress LLC Alizarine yellow R | 2243-76-7 | MFCD00007313 | 287.23 | C13H9N3O5 | 250 MG
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Alizarine Yellow R is an azo dye used primarily as a pH indicator and biological stain. This entry describes the 250 mg research reagent form (CAS 2243-76-7) with molecular formula C13H9N3O5 and molecular weight 287.23.
- Used as a pH indicator and biological stain.
- Azo dye with molecular formula C13H9N3O5 and molecular weight 287.23.
- Supplied as a 250 mg pack suitable for laboratory research.
- CAS number 2243-76-7 for unambiguous identification.
- Purity or dye content not specified on the manufacturer's datasheet.
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Medchemexpress LLC Cyclophilin inhibitor 1 | 1509904-96-4 | 99.5% | 593.67 | 25 MG
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Cyclophilin inhibitor 1 is a potent and orally bioavailable cyclophilin A inhibitor, with a Kd of 5 nM, and shows effective anti-HCV activity, with an EC50 of 98 nM for HCV 2a.
- Potent and orally bioavailable cyclophilin A inhibitor.
- Kd of 5 nM for cyclophilin A.
- Effective anti-HCV activity, with an EC50 of 98 nM for HCV 2a.
- Appearance: Solid, white to off-white.
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Medchemexpress LLC Tie2 kinase inhibitor 1 | 948557-43-5 | 99.8% | 439.53 | C26H21N3O2S | 1 ML
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Tie2 kinase inhibitor 1 is a potent, selective small-molecule inhibitor of the Tie2 receptor tyrosine kinase with reported anti-cancer activity. It inhibits Tie2 with an IC50 of 250 nM and is supplied for research use.
- Potent Tie2 inhibition with IC50 of 250 nM.
- High purity suitable for research applications (reported 99.8%).
- Characterized small molecule: formula C26H21N3O2S, molecular weight 439.53.
- Physical form light yellow to yellow solid.
- Available as concentrated solution for assay convenience.
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LaMarKa Chemical Company Standard #3 CA 1 PPM, Mg 1 PPM, FE 1 PPM (Contains Nitric Acid)
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Standard #3 Ca 3 Ppm, Mg 3Ppm, Fe 3 Ppm (Contains Nitric Acid)-Bottle Liter Plasti
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Pickering Laboratories Inc Artificial Saliva, Fusayama/Mayer, Custom pH, Not Stabilized, each (200 mL/bottle)
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This ready-to-use solution closely resembles themineral composition of natural saliva and can be usedfor testing a wide variety of products, including dentalmetal alloys. This formulation is at pH 4.9 and shouldbe stored refrigerated.
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Medchemexpress LLC Cyclophilin inhibitor 1 | 1509904-96-4 | 99.6% | 593.67 | 10 MG
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Cyclophilin inhibitor 1 is a potent and orally bioavailable cyclophilin A inhibitor, with a Kd of 5 nM, shows effective anti-HCV activity, with an EC50 of 98 nM for HCV 2a.
- Potent and orally bioavailable cyclophilin A inhibitor.
- Shows effective anti-HCV activity.
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Medchemexpress LLC Human PD-L1 inhibitor II | 2135542-85-5 | 98.3% | 2219.45 | 10 MG
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Human PD-L1 inhibitor II is a potent PD-L1 inhibitor with anti-cancer activity. It appears as a white to off-white solid.
- Potent PD-L1 inhibitor with anti-cancer activity
- White to off-white solid appearance
- Soluble in H2O at 25 mg/mL (11.26 mM) with ultrasonic assistance
- Ships at room temperature in continental US
- Powder storage: -80°C for 2 years, -20°C for 1 year (sealed, away from moisture and light, under nitrogen)
- In solvent storage: -80°C for 6 months, -20°C for 1 month (sealed, away from moisture and light, under nitrogen)
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LaMarKa Chemical Company Ceric Sulfate 0.1N (contains Sulfuric Acid)
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Ceric Sulfate 0.1N-Bottle Liter Plastic
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Cayman Chemical SodIM Phosphate Stock SolutI
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A concentrated buffer solution
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Apexbio Technology LLC LDN-193189 1062368-24-4 50mg
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LDN-193189 (CAS 1062368-24-4) is a selective small molecule inhibitor targeting type I bone morphogenetic protein (BMP) receptors specifically activin receptor-like kinase-2 (ALK2) and ALK3 It inhibits ALK2 and ALK3 with IC50 values of approximately 5 nM and 30 nM respectively In vitro studies using C2C12 cells demonstrated that LDN-193189 suppresses BMP-induced phosphorylation of Smad1/5/8 as well as p38 MAPK and Akt signaling Additionally research using bronchial epithelial (Beas2B) cells and murine models indicates that LDN-193189 prevents BMP2-induced E-cadherin downregulation and maintains epithelial barrier integrity LDN-193189 is thus valuable for studying BMP-mediated signaling pathways and related physiological processes
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