Antibody Panels and Kits
Cell Signaling Technology Mouse Microglia Marker IF Antibody Sampler Kit 1 Kit
Mouse Microglia Marker IF Antibody Sampler Kit 1 Kit
Biotium Bcl-6 (Follicular Lymphoma Marker)(BCL6/2497R), CF594 conjugate, 0.1mg/mL
Bcl-6 is a transcriptional repressor mainly required for germinal center (GC) formation and antibody affinity maturation which has different mechanisms of action specific to the lineage and biological functions. It forms complexes with different corepressors and histone deacetylases to repress the transcriptional expression of different subsets of target genes. Bcl-6 allows GC B-cells to proliferate very rapidly in response to T-cell dependent antigens and tolerate the physiological DNA breaks required for immunglobulin class switch recombination and somatic hypermutation without inducing a p53/TP53-dependent apoptotic response. Antibodies to Bcl-6 are helpful in a number of diagnostic settings, for example in the differential diagnosis of small B-cell lymphoma, and in distinguishing classical Hodgkin lymphoma from nodular lymphocyte predominant Hodgkin lymphoma (NLPHL).Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF
Cell Signaling Technology Double Strand Breaks (DSB) Repair Antibody Sampler Kit 1 Kit
Double Strand Breaks (DSB) Repair Antibody Sampler Kit 1 Kit
Cell Signaling Technology ALK Activation Antibody Sampler Kit 1 Kit
ALK Activation Antibody Sampler Kit 1 Kit
Cell Signaling Technology Human Reactive DNA Demethylation Antibody Sampler Kit 1 Kit
Human Reactive DNA Demethylation Antibody Sampler Kit 1 Kit
Biotium Bcl-6 (Follicular Lymphoma Marker) (BCL6/1475), CF568 conjugate, 0.1mg/mL
Bcl-6 is a transcriptional repressor mainly required for germinal center (GC) formation and antibody affinity maturation which has different mechanisms of action specific to the lineage and biological functions. It forms complexes with different corepressors and histone deacetylases to repress the transcriptional expression of different subsets of target genes. Bcl-6 allows GC B-cells to proliferate very rapidly in response to T-cell dependent antigens and tolerate the physiological DNA breaks required for immunglobulin class switch recombination and somatic hypermutation without inducing a p53/TP53-dependent apoptotic response. Antibodies to Bcl-6 are helpful in a number of diagnostic settings, for example in the differential diagnosis of small B-cell lymphoma, and in distinguishing classical Hodgkin lymphoma from nodular lymphocyte predominant Hodgkin lymphoma (NLPHL).Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dye
Cell Signaling Technology ApoE Synaptic Formation and Signaling Pathway Antibody Sampler Kit 1 Kit
ApoE Synaptic Formation and Signaling Pathway Antibody Sampler Kit 1 Kit
Abcam Embryonic Stem Cell Marker Panel (Human: Oct4, Nanog, Tra-1-60 (R), SOX2, SSEA4)
Embryonic Stem Cell Marker Panel (Human: Oct4, Nanog, Tra-1-60 (R), SOX2, SSEA4)
The product is subject to the following: Abcam Restricted Use Statement
Cayman Chemical NMDA Receptor NR1 Subunit Mon
Antigen: fusion protein containing amino acids 1-564 of the NR1 subunit of rat NMDA receptor • Host: mouse • Cross Reactivity: (+) rat and mouse NMDA receptor • Application(s): IP and WB • The NMDAR plays an essential role in memory, neuronal development and it has also been implicated in several disorders of the central nervous system including Alzheimer’s, epilepsy and ischemic neuronal cell death. The NR1 protein can form NMDA activated channels when expressed in Xenopus oocytes but the currents in such channels are much smaller than those seen in situ.
Cayman Chemical NMDA Receptor NR2B Subunit Po
Antigen: fusion protein from the C-terminus of the NR2B subunit of rat NMDA receptor • Host: rabbit • Cross Reactivity: (+) human, rat, and mouse NMDA receptor • Application(s): IHC, IP, and WB • Overexpression of the NR2B-subunit of the NMDA receptor has been associated with increases in learning and memory while aged, memory impaired animals have deficiencies in NR2B expression.
Biotium Bcl-2 (Apoptosis & Follicular Lymphoma Marker) (rBCL2/796), CF488A conjugate, 0.1mg/mL
This antibody recognizes a protein of 25-26 kDa, identified as Bcl-2. This antibody shows no cross-reaction with Bcl-x or Bax proteins. Bcl-2 suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. It regulates cell death by controlling the mitochondrial membrane permeability. Bcl-2 appears to function in a feedback loop system with caspases. It inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1). Expression of Bcl-2 inhibits programmed cell death (apoptosis). In most follicular lymphomas, neoplastic germinal centers express high levels of Bcl-2 protein, whereas the normal or hyperplastic germinal centers are negative. Consequently, this antibody is valuable when distinguishing between reactive and neoplastic follicular proliferation in lymph node biopsies. It may also be used in distinguishing between those foll
Biotium Bcl-6 (Follicular Lymphoma Marker) (BCL6/1718), CF594 conjugate, 0.1mg/mL
Bcl-6 is a transcriptional repressor mainly required for germinal center (GC) formation and antibody affinity maturation which has different mechanisms of action specific to the lineage and biological functions. It forms complexes with different corepressors and histone deacetylases to repress the transcriptional expression of different subsets of target genes. Bcl-6 allows GC B-cells to proliferate very rapidly in response to T-cell dependent antigens and tolerate the physiological DNA breaks required for immunglobulin class switch recombination and somatic hypermutation without inducing a p53/TP53-dependent apoptotic response. Antibodies to Bcl-6 are helpful in a number of diagnostic settings, for example in the differential diagnosis of small B-cell lymphoma, and in distinguishing classical Hodgkin lymphoma from nodular lymphocyte predominant Hodgkin lymphoma (NLPHL).Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. C