Substrates
Biotium NucView 488 Caspase-3 Substrate, 1mM in 1X PBS
NucView Caspase-3 Substrates are novel fluorogenic substrates for real-time or endpoint detection of apoptosis in live cells. The non-toxic, no-wash substrates do not inhibit caspase-3 unlike other caspase substrates or FLICA assays permitting multiday analysis. They consist of a high-affinity DNA dye linked to a DEVD caspase-3 substrate moiety. Initially non-fluorescent, the cell permeable substrate is cleaved by caspase-3 in apoptotic cells and emits fluorescence, for detection of caspase-3 activity and apopototic nuclear morphology. Suitable for flow cytometry, fluorescence microscopy, or live cell imaging systems, staining is compatible with fixation and permeabilization for immunostaining. NucView 488 is validated in over 100 cell types and 200 publications. Available with blue (NucView 405), green (NucView 488), or red (NucView 530) fluorescence, as PBS solutions for DMSO-sensitive cells, and as stand-alone assays or in kits with other apoptosis or necrosis probes.
Abcam ATP-gamma-S, Kinase substrate, 100UG
ATP-gamma-S is a kinase substrate and inhibitor of ATP-dependent enzyme systems. Hydrolyzed very slowly by phosphatases and most ATPases. Once thiophosphorylated, proteins are resistant to protein phosphatases. P2 purinergic receptor agonist. - Cited in over 30 publications - Purity > 80% - Soluble in water to 10 mM
The product is subject to the following: Abcam Restricted Use Statement
Avanti Polar Lipids BRAIN PL (4 5) P2 IN CHLOR 1MG
Brain PI(4,5)P2,L-a-Phosphatidylinositol-4,5-bisphosphate (Brain,Porcine-Triammonium Salt),1 mg, Molecular Weight: 1,098.19,Molecular Formula: C47H94N3O19P3,Percent Composition: C 51.40% H 8.63% N 3.83% O 27.68% P 8.46%
Revvity Health Sciences Inc LANCE Ultra ULight Anti-GST Antibody, 1nmole
LANCE Ultra ULight Anti-GST Antibody, 1nmole
Cayman Chemical LIpase Substrate 1.2mL
This assay kit provides the convenience of an all-inclusive cell-based reporter assay system for M-CSFR signaling. In addition to Reporter Cells included are an optimized culture medium for use in reviving the cryopreserved cells a culture medium for use in preparing test sample treatments the physiological activator M-CSF as a positive control Luciferase Detection Reagents and a cell culture-ready assay plate
Cayman Chemical PGE2 Substrate 250uL
A PDGFR and FGFR inhibitor (IC50s 5.35 4.6 28 28 and 78 nM for PDGFRa PDGFRB FGFR1 -2 and -3 respectively) selective for these kinases over FGFR4 (IC50 >1000 nM) but also inhibits c-Kit VEGFR2 VEGFR1 and IGF-1R (IC50s 67 33 36 and 75 nM respectively) as well as EGFR BTK Cdk4/cyclin D3 and MET (IC50s 128 198 214 and 396 nM respectively) inhibits the proliferation of MG-63 U2OS MNNG/HOS and Saos-2 cells (IC50s 0.84 0.76 1.36 and 0.72 UM respectively) inhibits the migration and invasion of U87MG and LN-229 cells at 0.3 and 0.5 UM decreases tumor volume and increases survival in a U87MG orthotopic mouse xenograft model 30 mg/kg
Aat Bioquest D-Luciferin potassium salt CAS 115144-35-9 (100 mg)
Luciferin is the most popular and versatile bioluminescent substrate. This catalog is for 100 mg.
Aat Bioquest D-Luciferin potassium salt CAS 115144-35-9 (1 g)
Luciferin is the most popular and versatile bioluminescent substrate. This catalog is for 1 g.
Cayman Chemical D-LucIferIn 100mg
A chemiluminescent substrate of firefly luciferase which produces light upon oxidative decarboxylation in the presence of ATP
Echelon Biosciences Research Labs PPLases Substrate, calorimetric - 10 mg, CAS#: 70967-97-4
PPLases Substrate, calorimetric - 10mg , Succinyl-Ala-Leu-Pro-Phe-pNA Category/Application: Enzyme Substrates This item is non returnable
Surmodics Inc TMB Enhanced HRP Membrane Substrate 100ml
The BioFX™ one component 3,3’,5,5’-tetramethylbenzidine (TMB) substrate is supplied in a ready-to-use solution for membrane applications. A highly intense staining pattern increases the signal-to-noise ratios for improved sensitivity in western blot, dot blots and line assays.
Enzo Life Sciences 7-Ethoxyresorufin (10mg). CAS: 5725-91-7
Fluorimetric substrate for cytochrome P450 IA1. Inhibits vasorelaxant responses to acetylcholine. Alternative name: 7-ER. Purity: ≥98%. Solubility: Soluble in DMSO (5mg/ml) or 100% ethanol (5mg/ml). Long Term Storage: Ambient.
Enzo Life Sciences OMNIMMP RED fluorogenic substrate (100µg)
Highly-quenched, ultra-bright fluorogenic substrate for most MMPs. 6’-TAMRA fluorescence is thoroughly quenched by the TQ3 group until cleavage by MMPs separates the two moieties. The OMNIMMP RED substrate offers key advantages over other MMP substrates. Purity: ≥90% (HPLC). Solubility: Soluble in DMSO (50mM). Long Term Storage: -20°C.
Enzo Life Sciences Z-RR-AMC (50mg). CAS: 88937-61-5
Fluorogenic substrate specific for cathepsin B (kcat/Km=105 M-1s-1). The following proteases do not cleave, or inefficiently cleave, this substrate: papain, cathepsins C/DPP-I, F, H, K/O2, L, L2/V, O, S, X/Z. Ex.: 365 nm, Em.: 440 nm, although the following Ex/Em can also be used: 355,380/450,460. This substrate is useful for analysis of cathepsin B activity in cell extracts, inhibitor screening, and kinetic analysis. Also available: fluorogenic calibration standard AMC (BML-KI144). Alternative name: Z-Arg-Arg-AMC. Purity: ≥98%. Long Term Storage: -20°C.