Isotopically Labeled Compounds
Medchemexpress LLC Adamantane-d16 | 30470-60-1 | 50 MG
Adamantane-d16 is the deuterium-labeled version of Adamantane. Adamantane is a polycyclic cage molecule known for its high symmetry and distinctive properties. It can be incorporated into the lipophilic part of lipid bilayers that form membranes and used as an anchor in the lipid bilayer of liposomes.
- Utilized in research for surface recognition and drug delivery.
- Can be used as a tracer for quantitation during drug development.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Deuteration has potential to influence the pharmacokinetic and metabolic profiles of drugs.
American Radiolabeled Chemicals Inc TRANS, TRANS-FPP (1-3H) 250UCL
pyrophosphate [1-3H] triammonium salt
Medchemexpress LLC Valsartan-d9 | 1089736-73-1 | 99.3% | 444.57 | 1 MG
Valsartan-d9 is deuterium labeled valsartan, an angiotensin II receptor antagonist with potential applications in high blood pressure and heart failure research.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Medchemexpress LLC Isovaleric acid-d7 | 1219805-32-9 | 99.5% | 109.17 | 5 MG
Isovaleric acid-d7 is the deuterium labeled Isovaleric acid. Isovaleric acid is a natural fatty acid and known to effect on neonatal death and possible Jamaican vomiting sickness in human.
- This compound can be used as a tracer.
- This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Medchemexpress LLC D-Fructose-13C-1 | 117013-19-1 | 25 MG
D-Fructose-13C-1 is the 13C labeled D-Fructose, a naturally occurring monosaccharide found in many plants. It is intended for research use only.
- Can be used as a tracer.
- Functions as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Stable heavy isotope of carbon-13.
Medchemexpress LLC Prometon-d14 | 1219803-45-8 | 239.38 g·mol⁻¹ | C10H5D14N5O | 1 MG
Prometon-d14 is the deuterium-labeled analogue of prometon supplied as a stable-isotope reference standard for analytical chemistry. It is intended for use as an internal standard in quantitative mass spectrometry and other analytical methods that require isotopically labeled tracers. CAS number 1219803-45-8; molecular formula C10H5D14N5O.
- Deuterium-labeled reference for accurate quantitation.
- Intended for use as an internal standard in LC-MS methods.
- Enables clear mass differentiation from native analytes.
- Provided in small, premeasured quantities suited to analytical workflows.
- Accompanied by molecular data for traceability in experiments.
Medchemexpress LLC Ponesimod-d7 100ug | 100UG
Ponesimod-d7 (ACT-128800-d7) is the deuterium-labeled Ponesimod (HY-10569) Ponesimod-d7 (ACT-128800) is a potent selective and orally active agonist of S1P1 with an IC50 of 6 nM in a radioligand binding assay Ponesimod-d7 activates S1P1-mediated signal transduction with high potency (EC50 5 7 nM) Ponesimod-d7 can protect against lymphocyte-mediated tissue inflammation[1 [2 [3
Cambridge Isotope Laboratories ETHYL ACETATE (2-13C, 99%), 1 G, 58735-82-3
ETHYL ACETATE (2-13C, 99%), 1 G, 58735-82-3
Medchemexpress LLC Quinoline-d7 | 34071-94-8 | MFCD00145200 | 98.3% | 136.2 g/mol | C9D7N | 50mg
Quinoline-d7 is the deuterium labeled Quinoline[1]
Medchemexpress LLC Maprotiline-d5 hydrochloride | 1794942-12-3 | 1 MG
Maprotiline-d5 hydrochloride is a deuterium-labeled version of Maprotiline hydrochloride, functioning as a selective noradrenalin re-uptake inhibitor and a tetracyclic antidepressant. This compound is suitable for various quantitative analyses due to its stable heavy isotopes.
- Used as a tracer
- Functions as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Stable heavy isotopes for drug development tracing
- Potential to affect pharmacokinetic and metabolic profiles of drugs
Medchemexpress LLC L-Tyrosine-d2-1 | 30811-19-9 | 183.20 | 100 MG
L-Tyrosine-d2-1 is the deuterium labeled L-Tyrosine, a non-essential amino acid that can inhibit citrate synthase activity in the posterior cortex.
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Medchemexpress LLC Simvastatin-d3 | 1002347-61-6 | 98.6% | 421.58 | 1 MG
Simvastatin-d3 is the deuterium-labeled Simvastatin. Simvastatin (MK 733) is a competitive inhibitor of HMG-CoA reductase with a Ki of 0.2 nM. It is for research use only and not sold to patients.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process.
- Deuteration has the potential to affect the pharmacokinetic and metabolic profiles of drugs.
Cambridge Isotope Laboratories PYRIDOXINE:HCL (5-HYDROXYMETHYL-D2, 98%), 5 MG, 5027-82-7
PYRIDOXINE:HCL (5-HYDROXYMETHYL-D2, 98%), 5 MG, 5027-82-7
Medchemexpress LLC Glyburide-d11 | 1189985-02-1 | C23H17D11ClN3O5S | 1 MG
Glyburide-d11 is the deuterium labeled Glibenclamide, an orally active ATP-sensitive K+ channel (KATP) inhibitor. It is used for research related to diabetes and obesity. Glyburide-d11 inhibits P-glycoprotein, directly binds and blocks the SUR1 subunits of KATP, and inhibits the cystic fibrosis transmembrane conductance regulator protein (CFTR). It interferes with mitochondrial bioenergetics by inducing changes on membrane ion permeability and can induce autophagy.
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Inhibits P-glycoprotein
- Blocks SUR1 subunits of KATP
- Inhibits cystic fibrosis transmembrane conductance regulator protein (CFTR)
- Interferes with mitochondrial bioenergetics
- Can induce autophagy