Isotopically Labeled Compounds
Medchemexpress LLC Thymidine-d3 | 74848-84-3 | MFCD01317525 | 99.8% | 245.25 | C10H11D3N2O5 | 10 MG
Thymidine-d3 is the deuterium-labeled analogue of thymidine used as a DNA synthesis inhibitor and cell-synchronizing agent. It is commonly used as a tracer or internal standard for quantitative analysis by NMR, GC-MS, or LC-MS, and to arrest cells at the G1/S boundary in cell cycle studies.
- High chemical and isotopic purity (99.8%).
- Suitable as a tracer and internal standard for NMR, GC-MS, and LC-MS.
- Effective for cell synchronization by arresting cells at the G1/S boundary.
- Solid powder form with recommended cold storage for stability.
- Available in small research pack sizes including 10 mg for analytical work.
Medchemexpress LLC 1,3,5-Triazine-2,4-diamine, 6-chloro-N-(ethyl-d5)-N'-(1-methylethyl)- | 163165-75-1 | 1 MG
Atrazine-d5 is deuterium labeled Atrazine, primarily used for controlling certain annual broadleaf and grass weeds. It inhibits photophosphorylation but typically does not cause lethality or permanent cell damage in the short term. Deuterium substitution can impact the pharmacokinetic and metabolic profiles of drugs, making this compound suitable for use as a tracer or an internal standard.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Stable heavy isotopes are incorporated for quantitation during drug development.
- Deuteration can affect pharmacokinetic and metabolic profiles of drugs.
Medchemexpress LLC Desoxycarbadox-d3 | 1448350-02-4 | 99.8% | 233.24 | 1 MG
Desoxycarbadox-d3 is the deuterium labeled Desoxycarbadox, a metabolite of Carbadox. Carbadox is a quinoxaline-di-N-oxide antibiotic compound. Desoxycarbadox-d3 can be used as a tracer and as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS. Deuterium labeling has potential to affect the pharmacokinetic and metabolic profiles of drugs.
- Deuterium labeled compound
- Metabolite of carbadox
- Quinoxaline-di-N-oxide antibiotic compound
- Useful as a tracer
- Serves as an internal standard for quantitative analysis
- Solid appearance
- White to off-white color
Medchemexpress LLC Octanal-d16 | 1219794-66-7 | 5 MG
Octanal-d16 is a deuterium-labeled octanal, a fragrant aldehyde known for its antioxidant and antibacterial properties. It has shown antifungal effects against *G. citri-aurantii* by disrupting cell membrane integrity and causing cellular component leakage. Furthermore, Octanal exhibits cytotoxicity towards HeLa cells, with an IC50 value of 3.5 μg/mL.
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Stable heavy isotopes have the potential to affect the pharmacokinetic and metabolic profiles of drugs
Medchemexpress LLC D-Fructose-4-13C | 84270-09-7 | 5 MG
D-Fructose-4-13C is the 13C labeled D-Fructose, a naturally occurring monosaccharide found in many plants.
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Cambridge Isotope Laboratories CHLOROFORM-D (D, 99.8%) +1% V/V TMS + SILVER FOIL, 100 G, 865-49-6
CHLOROFORM-D (D, 99.8%) +1% V/V TMS + SILVER FOIL, 100 G, 865-49-6
Medchemexpress LLC Malonyl CoA lithium | 108347-84-8 | 98.0% | 1 MG
Malonyl CoA lithium is an inhibitor of carnitine palmitoyl transferase 1 (CPT1). High Malonyl CoA lithium concentrations suppress fatty acid oxidation, while low Malonyl CoA lithium concentrations are permissive for fat oxidation.
- Inhibitor of carnitine palmitoyl transferase 1 (CPT1).
- High concentrations suppress fatty acid oxidation.
- Low concentrations are permissive for fat oxidation.
Medchemexpress LLC Lyso-platelet-activating factor C-16-d4 | 201216-37-7 | 99.0% | C24H48D4NO6P | 100 UG
Lyso-PAF C-16-d4 is the deuterium labeled Lyso-PAF C-16. Stable heavy isotopes, such as deuterium, are incorporated into drug molecules for quantitation during drug development processes, with the potential to affect pharmacokinetic and metabolic profiles.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Medchemexpress LLC Uridine-13C | 201996-62-5 | 99.8% | 1 MG
Uridine-13C is the 13C labeled Uridine. It is used as a tracer and an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS. Stable heavy isotopes of hydrogen, carbon, and other elements are incorporated into drug molecules primarily as tracers for quantitation during the drug development process.
- Used as a tracer
- Functions as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Incorporates stable heavy isotopes of hydrogen, carbon, and other elements
- Potential to affect pharmacokinetic and metabolic profiles of drugs through deuteration
Medchemexpress LLC (±)12(13)Epoxy-9Z-octadecenoic-9,10,12,13-d4 acid | 99.0% | 300.47 | 50 UG
(±)12(13)-EpOME-d4 is a deuterium labeled stable isotope of (±)12(13)-EpOME. It is designed for research purposes, particularly as a tracer and internal standard in quantitative analysis methods such as NMR, GC-MS, or LC-MS.
- Used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Deuterium labeling can affect pharmacokinetic and metabolic profiles of drugs
- Appears as a colorless to light yellow liquid
- Molecular formula: C18H28D4O3
Medchemexpress LLC Meglutol-d3 | 59060-36-5 | 98.0% | 5 MG
Meglutol-d3 is the deuterium labeled Meglutol. Meglutol is an antilipemic agent which lowers cholesterol, triglycerides, serum beta-lipoproteins and phospholipids, and inhibits the activity of hydroxymethylglutarryl CoA reductases, which is the rate limiting enzyme in the biosynthesis of cholesterol.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
Medchemexpress LLC Mephenytoin-d5 | 1185032-66-9 | >98.72% | 1 MG
Mephenytoin-d5 is a deuterium labeled form of Mephenytoin, an anticonvulsant that acts as a substrate for CYP2C19 and CYP2B6. It is commonly utilized as a tracer and internal standard for quantitative analysis methods such as NMR, GC-MS, or LC-MS.
- Can be used as a tracer for quantitative analysis
- Can be used as an internal standard for quantitative analysis
- Deuteration may affect pharmacokinetic and metabolic profiles
Cambridge Isotope Laboratories ETHYLENE (TRANS-1,2-D2, 98%), 1 L, 1517-53-9
ETHYLENE (TRANS-1,2-D2, 98%), 1 L, 1517-53-9
Medchemexpress LLC Balsalazide-d4 | 2714315-25-8 | 361.34 | C17H11D4N3O6 | 10 MG
Balsalazide-d4 is a deuterium-labeled analogue of balsalazide intended for use as an analytical/internal standard and research reagent in biochemical and pharmacological studies, particularly those involving interleukin and STAT3 signaling. It is supplied as a 10 mg solid with documented storage and solubility information to support analytical workflows.
- Deuterium-labeled isotopic standard for analytical assays
- Provided as 10 mg of solid suitable for LC-MS and quantitative analysis
- Molecular formula C17H11D4N3O6; molecular weight 361.34
- Soluble in DMSO at 50 mg/mL; ultrasonic assistance may be required
- Storage guidance: powder at -20°C (3 years) or 4°C (2 years); in solvent at -80°C (6 months)
- Suitable for metabolic tracing, quantitation, and mechanism-of-action studies