Apalutamide-13C,d3 is a 13C- and deuterium labeled form of Apalutamide (ARN-509), a potent and competitive androgen receptor (AR) antagonist. This compound incorporates stable heavy isotopes of hydrogen, carbon, and other elements, making it suitable for quantitative analysis during drug development processes. Deuteration has also garnered attention for its potential to affect the pharmacokinetic and metabolic profiles of drugs.
- Potent and competitive androgen receptor (AR) antagonist.
- Binds AR with an IC50 of 16 nM.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.