Antibody-Binding Proteins and Conjugates
Cayman Chemical FosInoprIlsodIum salt 50mg
An internal standard for the quantification of cholic acid by GC- or LC-MS
Cayman Chemical ArachIdIc AcIdodIum salt 50mg
An internal standard for the quantification of tenofovir by GC- or LC-MS
Cayman Chemical AzlocIlInsodIum salt 500mg
A potent antagonist of the PAF receptor inhibiting aggregation of rabbit and human platelets induced by PAF with IC50 values of 75 and 170 nM respectively prevents PAF-induced hypotension in rats while not blocking hypotension triggered by arachidonic acid histamine bradykinin or isoproterenol
Cayman Chemical TInptInsodIum salt 500mg
A cell-permeable inhibitor of SCF-mediated c-kit activation completely blocking phosphorylation of c-kit in human melanoma cells at a concentration between 1 and 5 UM prevents SCF-mediated downstream phosphorylation of p44/p42 ERK
Cayman Chemical D-LucIferInsodIum salt 50mg
5-(2-Aminopyridyl)amide oxime is a synthetic intermediate useful for pharmaceutical synthesis
Cayman Chemical CefoxItInsodIum salt 500mg
A potent inhibitor of GSK3B (IC50 22 nM) preventing tau phosphorylation both in vitro and in vivo
Cayman Chemical BucladesInsodIum salt 50mg
A cell permeable inhibitor of kinases that have been mutated by a single base substitution to become analog sensitive (as) as compared to the wild type kinase inhibits v-Src-as1 with an I338G substitution preferentially over v-Src (IC50 4.2 nM versus 28 M respectively) used to elucidate functions of several kinases in both mammalian and yeast systems
Cayman Chemical DIdodIum salt 50mg
A natural phytochemical that has anti-cancer effects at least in part through inhibition of NF-KB and Akt signaling pathways
Cayman Chemical 1-thIoD-GlucosesodIum sa 500mg
An a-methylated analog of 2C-B-FLY and the dihydrofuran analog of DOB a potent agonist of 5-HT2A and 5-HT2C intended for forensic and research purposes
Cayman Chemical LFolInIc AcIdcalcIM salt 500mg
A dual inhibitor of FAK1 (IC50s 2 0 and 80 nM for in vitro enzyme and cellular inhibition respectively) and ALK (IC50s 3 1 and 22 nM for in vitro enzyme and cellular inhibition respectively) blocks the proliferation of breast cancer cell lines in vitro or in vivo
Cayman Chemical OlsalazInsodIum salt 500mg
A cell-permeable inhibitor of PCSK9 secretion (IC50 4 8 UM) promotes the uptake of LDL cholesterol in hepatoma cells by increasing LDL receptor levels
Cayman Chemical EtIdronatesodIum salt 500mg
An affinity probe which allows carbaprostacyclin to be detected in complexes with transmembrane receptors and/or nucleic or protein binding partners
Cayman Chemical PIperacIlInsodIum salt 500mg
A potent inhibitor of class I PI3K isoforms (IC50 values of 5 27 7 and 14 nM for PI3Ka B and Y respectively) and mTOR (Ki 17 nM) induces cell cycle arrest or apoptosis in a range of cancer cell lines effective in vivo suppressing the growth of a number of tumor xenografts in mice