Custom Gene Expression Products
New England Biolabs, Inc. Authenticase - 25 reactions
Authenticase is a mixture of enzymes capable of recognizing mismatch and indel regions on a double-stranded DNA and creating double-stranded cleavages around these regions and with a limited non-specific activity on homoduplex regions of DNA. The regions of mismatch or indel could range from at least 1 to 10 bps. The activity of cleavage on mismatch/Indel regions can be utilized in the process of oligo-based PCR gene synthesis to improve the accuracy of PCR amplicons. Alternatively, Authenticase treated products can be analyzed to determine the popularity of heteroduplex of a PCR pool amplified from enzyme-based edited genome.
American Research Products Inc SEAP REPORTER GENE KIT CV0010
5000265237 SEAP REPORTER GENE KIT CV0010
Revvity Health Sciences Inc twinlite glow Reporter Gene Assay System, 100 Assay Points
twinlite glow Reporter Gene Assay System, 100 Assay Points
Leica Biosystems Protein Gene Product 9.5 Liquid Concentrate 1ml
Protein Gene Product 9.5 Liquid Concentrate 1ml
BIOHIPPO h BID shRNA Set RFP BSD
h BID shRNA Set (RFP BSD) shRNA lentiviral vector expressing RFP with Blasticidin selection for studies in Human Each vial provides a nominal titer of 5x10E6 (sh-mix) 5x10E6 (scr-mix) transducing units TU Validated human BID shRNA Lentivirus High-titer shRNA lentiviral particles specific for human BH3 interacting domain death (BID) The shRNA has been validated to meet or exceed 70% BID knockdown efficiency using a specific fluorescence-based method that is more rapid and reliable than qPCR The shRNA lentivirus is ultra-purified and concentrated to high-titer by PEG precipitation and sucrose gradient centrifugation and ideal for transducing difficult-to-transfect cells including thawed and/or primary cells Order a shRNA lentivirus set and receive lentivirus produced from mix of 2 independent shRNAs validated to knockdown the target gene ( 70%) plus control lentivirus produced from mix of 2 scrambled shRNA constructs
BIOHIPPO NF B-GFP-Luc-BSD LV
NF B-GFP-Luc-BSD is a transcription factor reporter lentiviral vector designed to monitor NF B signaling pathway in living cells The construct carries a GFP and luciferase dual reporter under the control of pathway responsive elements and includes a blasticidin selection marker to generate stable cell pools The lentivirus is provided as a ready to use VSV G pseudotyped preparation for efficient gene delivery and stable genomic integration Each vial provides a nominal titer of 5x10E6 transducing units TU Typical applications include pathway activation studies assay development compound screening and mechanism of action research The system is suitable for human and mouse cells and can be read using standard fluorescence microscopy flow cytometry or luciferase assays depending on the reporter gene This product is intended for research use only and is not for diagnostic or therapeutic procedures
ABclonal Technology Phospho-LRP6-S1490 Rabbit pAb
This gene encodes a member of the low density lipoprotein (LDL) receptor gene family. LDL receptors are transmembrane cell surface proteins involved in receptor-mediated endocytosis of lipoprotein and protein ligands. The protein encoded by this gene functions as a receptor or, with Frizzled, a co-receptor for Wnt and thereby transmits the canonical Wnt/beta-catenin signaling cascade. Through its interaction with the Wnt/beta-catenin signaling cascade this gene plays a role in the regulation of cell differentiation, proliferation, and migration and the development of many cancer types. This protein undergoes gamma-secretase dependent RIP- (regulated intramembrane proteolysis) processing but the precise locations of the cleavage sites have not been determined.
BIOHIPPO h/m IGF1R shRNA Set RFP BSD
h/m IGF1R shRNA Set (RFP BSD) shRNA lentiviral vector expressing RFP with Blasticidin selection for studies in Human/Mouse Each vial provides a nominal titer of 5x10E6 (sh-mix) 5x10E6 (scr-mix) transducing units TU Validated IGF1R shRNA Lentivirus High-titer shRNA lentiviral particles specific for human/mouse insulin like growth factor receptor (IGF1R) The shRNA has been validated to meet or exceed 70% IGF1R knockdown efficiency using a specific fluorescence-based method that is more rapid and reliable than qPCR The shRNA lentivirus is ultra-purified and concentrated to high-titer by PEG precipitation and sucrose gradient centrifugation and ideal for transducing difficult-to-transfect cells including thawed and/or primary cells Order a shRNA lentivirus set and receive lentivirus produced from mix of 2 independent shRNAs validated to knockdown the target gene ( 70%) plus control lentivirus produced from mix of 2 scrambled shRNA constructs
BIOHIPPO MYB-TAG-BSD LV
MYB-TAG-BSD is a transcription factor reporter lentiviral vector designed to monitor the target signaling pathway in living cells The construct carries a fluorescent reporter gene under the control of pathway responsive elements and includes a blasticidin selection marker to generate stable cell pools The lentivirus is provided as a ready to use VSV G pseudotyped preparation for efficient gene delivery and stable genomic integration Each vial provides a nominal titer of 5x10E6 transducing units TU Typical applications include pathway activation studies assay development compound screening and mechanism of action research The system is suitable for human and mouse cells and can be read using standard fluorescence microscopy flow cytometry or luciferase assays depending on the reporter gene This product is intended for research use only and is not for diagnostic or therapeutic procedures
OriGene LENTIORF CONTROL PARTICLES OF
LentiORF control particles of pLenti-C-Myc-DDK-P2A-Puro, >1x10^7 TU/ml, 0.5 ml
AdipoGen SARS-CoV-2 S1 RBDFc B1351
Recombinant protein. Receptor-binding domain RBD of SARS-CoV-2 Spike protein S1 aa 319-541 containing the mutations K417N, E484K, N501Y is fused to the N-terminus of the Fc region of human IgG1. Endotoxin <0.01EU/µg purified protein LAL test. Lyophilized. Contains PBS. SARS-CoV-2 shares 79.5% sequence identity with SARS-CoV and is 96.2% identical at the genome level to the bat coronavirus BatCoV RaTG133, suggesting it had originated in bats. The coronaviral genome encodes four major structural proteins the Spike S protein, Nucleocapsid N protein, Membrane/Matrix M protein and the Envelope E protein. The SARS Envelope E protein contains a short palindromic transmembrane helical hairpin that seems to deform lipid bilayers, which may explain its role in viral budding and virion envelope morphogenesis. The SARS Membrane/Matrix M protein is one of the major structural viral proteins.