AdipoGen Fc LALA-PG-KIHIrisin mono
Recombinant protein. Fc LALA-PG KnobsIrisin human, aa 32-143 /mouse, aa 29-140 and Fc LALA-PG Holes form the Fc LALA-PG-KIH humanIrisin monomeric rec. using the Knobs-into-Holes technology see reference J.B. Ridgway, et al. Protein Eng. 9, 617 1996. Source HEK 293 cells. Lyophilized. Contains PBS Irisin is a recently described exercise-induced hormone secreted by skeletal muscle in mice and humans. Irisin activates beige fat cells beige cells have a gene expression pattern distinct from either white or brown fat and are preferentially sensitive to the polypeptide hormone Irisin. Irisin is cleaved from the type I membrane protein FNDC5 and improves systemic metabolism by increasing energy expenditure.