Proteins and Derivatives
Cayman Chemical Cholesteryl Butyrate 10g
A cationic lipid lipoplexes containing R-DOTAP and encapsulating siRNA targeting CYP19A1 decrease aromatase activity in MCF-7 cells vaccination with an HPV 16 protein E7 peptide in R-DOTAP-containing liposomes induces IFN-Y production by CD8 T cells and TILs and decreases tumor size in a murine cervical cancer model subcutaneous immunization with recombinant influenza B hemagglutinin using R-DOTAP as an adjuvant increases IL-2 and IFN-Y production in CD4 T cells isolated from mouse draining lymph nodes and spleen
Cayman Chemical AsperosaponIn VI 50mg
A sesquiterpene with diverse biological activities inhibits PRV replication in Vero cells from 10-150 UM enhances doxorubicin-induced cytotoxicity and apoptosis in doxorubicin-resistant MCF-7/adr cells from 50-250 UM reduces body weight gain visceral fat pad weight serum insulin and plasma glucose levels and hepatic lipid levels in a mouse model of high-fat diet-induced obesity at 5 10 and 20 mg/kg decreases brain MDA levels and activity of SOD and GPX as well as reduces infarct volume in a rat model of MCAO-induced ischemia-reperfusion injury
Cayman Chemical AsperosaponIn VI 10mg
A sesquiterpene with diverse biological activities inhibits PRV replication in Vero cells from 10-150 UM enhances doxorubicin-induced cytotoxicity and apoptosis in doxorubicin-resistant MCF-7/adr cells from 50-250 UM reduces body weight gain visceral fat pad weight serum insulin and plasma glucose levels and hepatic lipid levels in a mouse model of high-fat diet-induced obesity at 5 10 and 20 mg/kg decreases brain MDA levels and activity of SOD and GPX as well as reduces infarct volume in a rat model of MCAO-induced ischemia-reperfusion injury
Cayman Chemical SIamenosIde I 25mg
A URAT1 inhibitor (IC50 0.025 UM for the human transporter) selective for human URAT1 over rat URAT1 (IC50 41 UM) as well as human OAT1 and OAT4 (IC50s 4.6 and 5.9 UM respectively)
Cayman Chemical CalpaIn InhIbItr III 10mg
A triacylglycerol containing heneicosaNIc acid groups at the sn-1 sn-2 and sn-3 positions has been used as an internal standard for the quantification of fatty acids in human breast milk samples and triacylglycerols in rat heart
Sigma Aldrich Fine Chemicals Biosciences Neutrophil Elastase Activi
Neutrophil Elastase (NE EC 3.4.21.37 leukocyte elastase ELANE ELA2 elastase 2 neutrophil elaszym or serine elastase) is a cytotoxic serine protease. It is stored in the azurophil granules of neutrophil granulocyte and is released following cell stimulation e.g. by pathogens immune complexes or chemotactic agents (PMA). Mutation in the gene ELA2 (neutrophil elastase) results in neutropenia a hereditary disorder characterized by reduced neutrophil count in an individual.
Sigma Aldrich Fine Chemicals Biosciences Lectin from Wisteria flori2MG
Lectin from Wisteria flori2MG
Sigma Aldrich Fine Chemicals Biosciences sIL 6 Receptor alpha human
Interleukin-6 (IL-6) mediates its biological effects through the type I IL-6 receptor system that consists of two chains IL-6RÎ and gp130. The IL-6RÎ chain is the binding component specific to IL-6 while the gp130 only transmits signals of IL-6 when bound to IL-6RÎ. IL-6R has a role in various signaling cascades. The gp130 also can transmit signals from leukemia inhibitory factor (LIf) oncostatin M (OSM) ciliary neurotrophic factor (CNTf) interleukin-11 (IL-11) and cardiotrophin-1 (CT-1) in conjunction with other receptor subunits. The low-affinity binding site for IL-6 is composed of IL-6RÎ alone. IL-6RÎ is expressed in a wide range of cells including T cells fibroblasts and macrophages. Soluble IL-6RÎ which consists of only the extracellular domain of the IL-6RÎ chain acts as an agonist of IL-6 activity at low concentrations. Recombinant human sIL-6RÎ is a 37.6kDa protein consisting of the extracellular domain of the IL-6RÎ chain (339 amino acid residues).
Sigma Aldrich Fine Chemicals Biosciences Thrombospondin 1 human rec
Recombinant human thrombospondin-1 is expressed in HEK293 cells as a glycoprotein with a calculated moleculaer mass of 127.5 kDa. This protein is manufactured in human cells using an all-human production system with no serum. The human cells expression system allows human-like glycosylation and folding and often supports better stability of the protein in culture.
Sigma Aldrich Fine Chemicals Biosciences Decorin from bovine articu5MG
Decorin from bovine articular cartilage is a proteoglycan that belongs to the small leucine-rich repeat proteoglycans and proteins (SLRPs) family. Decorin is present in almost all tissues. It has a protein core composed of leucine-rich repeats (LRRs) flanked by two cysteine-rich regions.
Cayman Chemical Cholesteryl Behenate 50mg
An analytical reference standard categorized as an opioid intended for research and forensic applications
Cayman Chemical Cholesteryl Oleate 500mg
A metabolite of ellagic acid with antiproliferative anti-inflammatory and anti-oxidant properties decreases proliferation in human endometrial cancer cell lines at a concentration of 1 UM arrests the cell cycle at the G2/M transition and modulates estrogen receptor-regulated gene expression potentiates the antiproliferative effect of 5-fluorouracil decreases PGE2 levels and prevents upregulation of COX-2 gene expression and protein levels in a rat model of colitis induces mitophagy improves fitness and extends lifespan of C. elegans increases exercise capacity in mice