Native Proteins and Derivatives
Biotium MAP3K1 Mitogen-Activated Protein Kinase Kinase Kinase 12F6 CF594 conjugate 0.1mgmL
MAP3K1 Mitogen-Activated Protein Kinase Kinase Kinase 12F6 CF594 conjugate 0.1mgmL
Biotium MAP3K1 Mitogen-Activated Protein Kinase Kinase Kinase 12F6 CF488A conjugate 0.1mgmL
MAP3K1 Mitogen-Activated Protein Kinase Kinase Kinase 12F6 CF488A conjugate 0.1mgmL
Bioworld PHOSPHOLIPASE A2 P00630 BEE
PHOSPHOLIPASE A2 P00630 BEE VENOM PROTEIN (RECOMBINANT): Recombinant Phospholipase A2 Bee Venom Protein (PA2-BVP)(EGF) Source: E.Coli Background: Description: E.coli derived recombinant. The protein contains phospholipase A2 bee ve...
AdipoGen Clusterin SF hrec
Protein. Signal peptide sequence and the human secretory clusterin aa 1-449 are fused at the C-terminus to a FLAG -tag. Source HEK 293 cells. Endotoxin content <0.01EU/µg purified protein LAL test Lonza. Lyophilized. Contains PBS. Purity >90% SDS-PAGE. Clusterin shares homology with the small heat shock protein family of molecular chaperones. The mature secreted form of the protein is a glycosylated, 80kDa disulfide-linked heterodimer of alpha and beta subunits produced by internal cleavage. Clusterin is expressed in virtually all tissues and found in all human fluids. It is involved in numerous physiological processes important for carcinogenesis and tumor growth, including apoptotic cell death, cell cycle regulation, DNA repair, cell adhesion, tissue remodeling, lipid transportation, membrane recycling and immune system regulation. Clusterin also exists as a nuclear protein.
Cayman Chemical CalpaIn InhIbItr III 10mg
A triacylglycerol containing heneicosaNIc acid groups at the sn-1 sn-2 and sn-3 positions has been used as an internal standard for the quantification of fatty acids in human breast milk samples and triacylglycerols in rat heart
Cayman Chemical 17mthyl StearIc ACD mthyl 20mg
A semisyntheticBlactam antibiotic active against clinical isolates of methicillin-susceptible S. aureus and penicillin-susceptible S. pneumoniae as well as group A group B and viridans group streptococci in vitro (MIC90s 0.06-2 Ug/ml) less effective toward other bacteria (MIC90 16 Ug/ml for S. epidermidis S. haemolyticus E. faecalis E. faecium MRSA and penicillin-intermediate and -resistant S. pneumoniae) targets the bacterial cell wall inhibits S. pneumoniae penicillin-binding proteins 1a 1b 2a 2b and 3 in vitro (IC50s 0.17-1.75 UM) inhibits growth of S. aureus in a thigh model of infection in mice (ED50 45.19 mg/kg s.c.)
Cayman Chemical CalpaIn InhIbItr II 25mg
A potent PLD2 inhibitor both in vitro (IC50 140 nM) and in cells (IC50 110 nM) also effective as a PLD1 inhibitor at higher concentrations (IC50 5.1 M in vitro 1.0 M in cells) strongly inhibits the invasive migration of breast cancer cells in transwell assays
Cayman Chemical CalpaIn InhIbItr I 5mg
A bioactive saponin from traditional Chinese medicine dose-dependently inhibits human adenovirus type 3 (HAdV-3) in A549 cells (IC50 23 UM LC50 865 UM) has diverse protective effects for the cardiovascular immune digestive and nervous systems reduces myocardial infarct size in dogs
Cayman Chemical PseudogInsenosIde F11 50mg
An internal standard for the quantification of norgestrel by GC- or LC-MS
Cayman Chemical 2 3-O- 5-ChloronthrnIloy 3.3mg
A JAK3 inhibitor (IC50 11 UM) inhibits FcεRI-mediated LTC4 and LTB4 release from and 5-LO translocation to the membrane in RBL-2H3 mast cells at 10 UM reduces airway hyperresponsiveness and BALF eosinophil infiltration in a mouse model of ovalbumin-induced allergic asthma at 12 and 40 mg/kg
Cayman Chemical SpGunosIn5O 1thIotrIp 2.7mg
An FLT3 inhibitor inhibits wild-type FLT3D835Y and FLT3-ITD (IC50s 13 8 and 3 nM respectively) suppresses the growth of MV4-11 AML cells that express FLT3-ITD (GI50 7 nM) induces cell cycle arrest at the G1 phase and apoptosis in the same cells reduces intratumor FLT3-ITD autophosphorylation in a MV4-11 mouse xenograft model at 10 mg/kg