Cell Culture Media, Supplements, and Reagents
Medchemexpress LLC HPRG Human HEK293 10ug | 10ug
HPRG protein is a multifunctional plasma glycoprotein with the ability to bind multiple ligands including heme heparin thrombospondin etc HPRG regulates immune processes angiogenesis coagulation and fibrinolysis through zinc-dependent binding to heparin and glycosaminoglycans HPRG Protein Human (HEK293 His) is the recombinant human-derived HPRG protein expressed by HEK293 with C-His C-10 His labeled tag
eMolecules 2767422-72-8 | Medchem Express | HS-276 | 5mg | 719836206 | HY-147141 | 419.529 | C24H29N5O2
Medchem Express | Isoliensinine | 5mg | 527573723 | HY-N0770 | 6817-41-0 | MFCD11042260 | 610.751 | C37H42N2O6
If you are unable to find the chemical you are looking for, make sure you are logged into your fishersci.com account and click on the following link:
eMolecules Building Block Tool<|a>
eMolecules 2115701-93-2 | Medchem Express | ()-JQ1 PA | 5mg | 446260419 | HY-112789 | 437.95 | C22H20ClN5OS
Ambeed | 1-Bromo-2-nitronaphthalene | 250mg | 572143832 | A674088 | 4185-55-1 | MFCD00971807 | 252.067 | C10H6BrNO2
If you are unable to find the chemical you are looking for, make sure you are logged into your fishersci.com account and click on the following link:
eMolecules Building Block Tool<|a>
eMolecules 1825352-65-5 | Medchem Express | Risdiplam | 5mg | 415686631 | HY-109101 | 401.474 | C22H23N7O
Ambeed | (4-(tert-Butoxycarbonyl)-5-chloro-2-fluorophenyl)boronic acid | 100mg | 714083920 | A1535265 | 2828439-64-9 | 274.480 | C11H13BClFO4
If you are unable to find the chemical you are looking for, make sure you are logged into your fishersci.com account and click on the following link:
eMolecules Building Block Tool<|a>
Apexbio Technology LLC SANT-1 304909-07-7 10mg
SANT-1 (CAS 304909-07-7) is a small molecule antagonist targeting the Smoothened (Smo) transmembrane protein a central component of the Hedgehog (Hh) signaling pathway Dysregulation of Smo activity is implicated in aberrant cell differentiation and proliferation contributing to oncogenesis High-throughput assays indicate that SANT-1 exhibits potent inhibition of Smo with IC50 values of 20 nM and 30 nM in Shh-LIGHT2 and SmoA1-LIGHT2 cell models respectively and demonstrates high binding affinity (KD 1 2 nM) In pancreatic cancer cell lines SANT-1 suppresses Panc-1 cell growth with an IC50 of 100 M Additionally co-administration with SAHA enhances anti-tumor effects via synergistic inhibition of Hh signaling SANT-1 serves as a valuable research tool for studying Hh pathway modulation and investigating combination therapeutic strategies in cancer models
Apexbio Technology LLC Lomeguatrib 192441-08-0 10mg
Lomeguatrib (CAS 192441-08-0) is a potent inhibitor of O6-alkylguanine-DNA methyltransferase (MGMT) an enzyme involved in DNA repair that mitigates the cytotoxic effects of alkylating agents In MCF-7 cells Lomeguatrib inactivates MGMT with an approximate IC50 of 6 nM By suppressing MGMT activity Lomeguatrib sensitizes MGMT-expressing cell lines such as A375P and select mutBRAF and mutNRAS melanoma models to temozolomide but does not alter sensitivity to dacarbazine Clinical investigations have demonstrated dose-dependent inactivation of MGMT in patient-derived tumor tissues and peripheral blood mononuclear cells highlighting Lomeguatrib s value as a research tool for studying MGMT-mediated resistance mechanisms in cancer
Medchemexpress LLC HY-111048 5mg Medchemexpress, Corin CAS:1808113-09-8 Purity:>98%
Medchemexpress, HY-111048 5mg Corin CAS:1808113-09-8 Corin is a dual inhibitor of histone lysine specific demethylase (LSD1) and histone deacetylase (HDAC) , with a K i (inact) of 110 nM for LSD1 and an IC 50 of 147 nM for HDAC1. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC HY-109567A 5mg Medchemexpress, Gemcabene (calcium) CAS:209789-08-2 Purity:>98%
Medchemexpress, HY-109567A 5mg Gemcabene (calcium) CAS:209789-08-2 Gemcabene calcium (PD-72953 calcium), a first-in-class lipid-lowering agent, lowers low-density lipoprotein cholesterol (LDL-C), decreases triglycerides, and raises high-density lipoprotein cholesterol (HDL-C) and lowers pro-inflammatory acute-phase protein, C-reactive protein (CRP), exerting anti-inflammatory activity [1] [2] [3] . Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC HY-111457 5mg Medchemexpress, BAY-677 CAS:2117404-84-7 Purity:>98%
Medchemexpress, HY-111457 5mg BAY-677 CAS:2117404-84-7 BAY-677 is an inactive control for BAY-678. BAY-678 is an orally bioavailable, highly potent, selective and cell-permeable inhibitor of human neutrophil elastase (HNE) , with an IC 50 of 20 nM [1] . BAY-678 is also nominated as a chemical probe to the public via the Structural Genomics Consortium (SGC) [2] . Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC HY-109567 10mg Medchemexpress, Gemcabene CAS:183293-82-5 Purity:>98%
Medchemexpress, HY-109567 10mg Gemcabene CAS:183293-82-5 Gemcabene (PD-72953), a first-in-class lipid-lowering agent, lowers low-density lipoprotein cholesterol (LDL-C), decreases triglycerides, and raises high-density lipoprotein cholesterol (HDL-C) and lowers pro-inflammatory acute-phase protein, C-reactive protein (CRP), exerting anti-inflammatory activity [1] [2] [3] . Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC HY-10395 5mg Medchemexpress, PD173955 CAS:260415-63-2 Purity:>98%
Medchemexpress, HY-10395 5mg PD173955 CAS:260415-63-2 Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC Nifurtimox | 23256-30-6 | MFCD00869254 | >=98.0% | 287.30 g/mol | C10H13N3O5S | 50 MG
Nifurtimox (CAS 23256-30-6) is supplied as a reference standard for research and analytical use, including assay development, method validation, and quality control. The product is accompanied by analytical data to confirm identity and purity for laboratory applications.
- Reference standard for assay development and quality control.
- Characterized molecular formula C10H13N3O5S and molecular weight 287.30.
- High purity suitable for analytical applications (≥98.0% reported).
- Supplied with a downloadable datasheet containing analytical and identity data.
- Stable solid form with standard storage and handling recommendations.
Lifeline Cell Technology M MEL HU LIFELINE KT
Includes BronchiaLife Basal Medium 485 mL, BronchiaLife SAE LifeFactors Kit. Optimized for the serum-free culture of human small airway epithelial cells. Supports the growth of these cells over a period of at least 15 population doublings.