Chloramphenicol palmitate is an orally active prodrug of Chloramphenicol, formed by the esterification of the agent with Palmitic acid. It is rapidly and completely hydrolyzed by intestinal esterase, releasing Chloramphenicol, which is an orally effective broad-spectrum antibiotic. For research use only. MedChemExpress (MCE) does not sell to patients.
- Orally active prodrug of Chloramphenicol.
- Rapidly and completely hydrolyzed by intestinal esterase.
- Releases Chloramphenicol, an orally effective broad-spectrum antibiotic.
- In vivo, chloramphenicol palmitate (10% dry formulation; p.o.; four doses) achieves steady-state plasma chloramphenicol concentrations of 5-6 μg/mL in four female beef-type calves, with an elimination half-life of 4.5 hours (chloramphenicol).