Cell Culture Media, Supplements, and Reagents
Medchemexpress LLC HY-116564 5mg Medchemexpress, Lotilaner CAS:1369852-71-0 Purity:>98%
Medchemexpress, HY-116564 5mg Lotilaner CAS:1369852-71-0 Lotilaner is a parasiticide, acts as a potent non-competitive antagonist of insects GABACl receptors, with an IC50 of 23.84 nM for Drosophila melanogaster GABA receptor. No effect on a dog GABAA receptor. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC Risdiplam | 1825352-65-5 | 99.6% | 401.46 | 50 MG
Risdiplam (RG7916) is an orally administered, centrally and peripherally distributed SMN2 pre-mRNA splicing modifier that increases survival motor neuron (SMN) protein levels. For research use only.
- Orally administered
- Centrally and peripherally distributed
- SMN2 pre-mRNA splicing modifier
- Increases survival motor neuron (SMN) protein levels
eMolecules 2070014-88-7 | Medchem Express | SRI-011381 (hydrochloride) | 5mg | 446255228 | HY-100347A | MFCD30377213 | 365.95 | C20H32ClN3O
AstaTech | (2-([(4-METHYL-1H-IMIDAZOL-5-YL)METHYL]THIO)ETHYL)AMINE 2HCL | 0.25g | 364323563 | S11912 | 95.000 | 38603-72-4 | MFCD12031495 | 244.180 | C7H15Cl2N3S
If you are unable to find the chemical you are looking for, make sure you are logged into your fishersci.com account and click on the following link:
eMolecules Building Block Tool<|a>
Medchemexpress LLC Hdac-in-4 | 1252003-13-6 | 98.0% | 335.40 g·mol-1 | C20H21N3O2 | 5 MG
HDAC-IN-4 is a small-molecule inhibitor selective for histone deacetylase isoforms HDAC6 and HDAC10, with reported cellular activity in BRET and FRET assays and demonstrated antitumoral effects in preclinical studies. Supplied as a solid in multiple milligram sizes or as a 10 mM solution in DMSO, it is intended for research use in biochemical and cellular assays.
- Selective inhibition of HDAC6 and HDAC10.
- pIC50 values of 7.2 (HDAC6) and 6.8 (HDAC10) in BRET assays.
- Observed activity in FRET assays against several HDAC isoforms.
- Available as small solid quantities and as a 10 mM solution in DMSO.
- High purity (98.0%) suitable for biochemical assays.
- Molecular weight 335.40 g·mol-1 and formula C20H21N3O2.
Medchemexpress LLC HY-111050 5mg Medchemexpress, JNJ-38877618 CAS:943540-74-7 Purity:>98%
Medchemexpress, HY-111050 5mg JNJ-38877618 CAS:943540-74-7 JNJ-38877618 is a potent, highly selective, orally bioavailable Met kinase inhibitor with IC50s of 2 and 3 nM for wild type and mutant Met, respectively. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC Ponatinib hydrochloride | 1114544-31-8 | 99.8% | 569.02 | 50 MG
Ponatinib hydrochloride (AP24534 hydrochloride) is a hydrochloride of ponatinib. It is an orally active multi-targeted kinase inhibitor with IC50s of 0.37 nM for Abl, 1.1 nM for PDGFRα, 1.5 nM for VEGFR2, 2.2 nM for FGFR1, and 5.4 nM for Src. This product offers several key features and benefits for research applications.
- Orally active multi-targeted kinase inhibitor
- IC50s: 0.24 nM for LYN, 0.37 nM for Abl, 1.1 nM for PDGFRα, 1.5 nM for VEGFR2, 2.2 nM for FGFR1, and 5.4 nM for Src
- Can reduce the viability, migration, and function of human endothelial cells in vitro
- Protects mice from lethal influenza infection by inhibiting cytokine storm in vivo
- Solid, off-white to light yellow appearance
- For research use only
Medchemexpress LLC Risdiplam | 1825352-65-5 | 99.0% | 401.46 | 1 MG
Risdiplam (RG7916) is an orally administered, centrally and peripherally distributed SMN2 pre-mRNA splicing modifier that increases survival motor neuron (SMN) protein levels. It modulates SMN2 pre-mRNA splicing towards the production of full-length SMN2 mRNA, thereby increasing functional SMN protein.
- Orally administered and distributed centrally and peripherally
- Modulates SMN2 pre-mRNA splicing
- Increases survival motor neuron (SMN) protein levels
- Leads to an increase in SMN2 full length transcript
- Suitable for laboratory centrifugation and storage
Medchemexpress LLC Ipatasertib-NH2 | 1001382-14-4 | 99.6% | 50 MG
Ipatasertib-NH2, also known as GDC-0068-NH2 or RG7440-NH2, functions as a ligand for the target protein AKT within PROTAC (INY-03-041). This PROTAC molecule is specifically designed by combining Ipatasertib-NH2 with a ten-hydrocarbon linker and a CRBN ligand, Lenalidomide, to facilitate E3 ubiquitin ligase activity.
- Purity of 99.6%
- Molecular weight of 415.92
- Chemical formula C21H26ClN5O2
- Appearance as a white to light yellow solid
- Soluble in DMSO at 100 mg/mL
- Recommended storage for powder: -20°C for 3 years, 4°C for 2 years
- Recommended storage in solvent: -80°C for 6 months, -20°C for 1 month
- Ligand for target protein AKT in PROTAC research
Medchemexpress LLC HY-B0323 100mg Medchemexpress, Sulfisoxazole CAS:127-69-5 Purity:>98%
Medchemexpress, HY-B0323 100mg Sulfisoxazole CAS:127-69-5 Sulfisoxazole (Sulfafurazole), an endothelin receptor antagonist, is a sulfonamide antibacterial with an oxazole substituent. Sulfisoxazole inhibits breast cancer exosome release by targeting endothelin receptor A. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC HY-16671 50mg Medchemexpress, CFTR(inh)-172 CFTR Inhibitor-172;CFTRinh-172 CAS:307510-92-5 Purity:98%
Medchemexpress,HY-16671 50mg CFTR(inh)-172 CFTR Inhibitor-172;CFTRinh-172 CAS:307510-92-5 Formula:C18H10F3NO3S2 CFTR(inh)-172 is a potent and selective blocker of the CFTR chloride channel; reversibly inhibited CFTR short-circuit current in less than 2 minutes with a Ki of 300 nM. Purity:98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Gold Biotechnology Inc Kanamycin Monosulfate Solution
Kanamycin is an aminoglycoside antibiotic isolated from Streptomyces kanamyceticus It is effective against gram-positive and gram-negative bacteria as well as Mycoplasma species Kanamycin is commonly used to select for bacteria that have been transformed with a kanamycin-resistant gene and plant tissues that have the NPT II ( APH3 ) gene incorporated in them Kanamycin is very soluble in aqueous solution and is typically used in concentrations of 50-100 g/ml
Medchemexpress LLC Sirolimus (rapamycin) | 53123-88-9 | MFCD00867594 | 99.0% | 914.17 | C51H79NO13 | 10 MG
Rapamycin (sirolimus) analytical standard supplied as a 10 mg reference material for research and analytical applications. It is intended for use in assay calibration, method validation, and analytical reference testing; for research use only.
- Analytical standard for rapamycin (sirolimus).
- Useful for assay calibration and method validation.
- Molecular formula C51H79NO13.
- Molecular weight 914.17.
- Supplied as a 10 MG reference quantity.
- Intended for research and analytical applications; not for clinical use.
Medchemexpress LLC HY-16231 5mg Medchemexpress, GGTI-2418 CAS:501010-06-6 Purity:>98%
Medchemexpress, HY-16231 5mg GGTI-2418 CAS:501010-06-6 GGTI-2418 is a highly potent, competitive, and selective geranylgeranyltransferase I ( GGTase I ) inhibitor. GGTI-2418 inhibits GGTase I and FTase activities with IC 50 s of 9.5 nM and 53 μM, respectively. GGTI-2418 also increases p27(Kip1) and induces significant regression of breast tumors [1] . Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Research Products International Corp Bleomycin Sulfate, 15 Milligrams
Bleomycin sulfate is an antibiotic derived from Streptomyces verticillus. It has found application in the field of cancer research and treatment. This antibiotic is a glycopeptide with DNA-cleaving properties. It is known for its ability to induce DNA strand breaks, making it effective in inhibiting the replication of cancer cells.
In research settings, bleomycin sulfate is utilized as a tool to study DNA damage and repair mechanisms. It is commonly employed in cell biology experiments to induce controlled DNA damage for the investigation of cellular responses and signaling pathways associated with DNA repair.