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For researchers, scientists, and technical professionals: Your one-stop shop for the complete range of laboratory, production, and safety products and services.
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JNJ-A07 is a highly potent inhibitor of Dengue virus (DENV) with an EC50 of 0 1 nM in the DENV-2 strain (16681) in Vero cells It exhibits antiviral activity by preventing the formation of the viral replication complex through blocking the interaction between two viral proteins NS3 and NS4B
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
(+)-JNJ-A07 is a highly potent, orally active pan-serotype dengue virus inhibitor that targets the NS3-NS4B interaction. It demonstrates nanomolar to picomolar activity against a panel of 21 clinical isolates. The compound possesses a favorable pharmacokinetic profile, leading to outstanding efficacy against dengue virus infection in mouse infection models.
Exhibits a high barrier to resistance
Prevents the formation of the viral replication complex by blocking the interaction between two viral proteins (NS3 and NS4B)
Potent and orally active pan-serotype dengue virus inhibitor
Effective against a panel of 21 clinical isolates
Favorable pharmacokinetic profile
Outstanding efficacy against dengue virus infection in mouse models
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
The 1 gallon Micro Cleaning Solution is used specially for ultrasonic cleaning machines, glass, metals, plastics and rubber. It can remove radioactive contaminants and contains no phosphates.
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More