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CC260 is a selective PI5P4Kα and PI5P4Kβ inhibitor with Kis of 40 nM and 30 nM, respectively. It does not inhibit or weakly inhibits other protein kinases, such as Plk1 and RSK2. This compound can be used for cell energy metabolism, diabetes and cancer research.
Enhances Insulin-induced Akt phosphorylation
Suppresses S6K phosphorylation by mTORC1
Significantly increases phosphorylation of acetyl-CoA carboxylase (ACC)
Reduces ability of cells to survive serum starvation
Causes an increase in glycolytic ATP production
Useful for cell energy metabolism, diabetes and cancer research
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
Neoline (Bullatine B) is a diterpenoid alkaloid used in preclinical research, reported to have neuroprotective and antinociceptive effects. It is supplied as a solid with high purity and is intended for laboratory applications.
Purity 98.0% suitable for research use.
Molecular weight 437.57 g/mol; formula C24H39NO6.
Available in small milligram quantities for in vitro and in vivo studies.
Solid form; store at 4°C and protect from light; in solution, store at -80°C for long term.
Synonym: Bullatine B.
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More