Hs00127739_cn

• Gene Symbol: AGTR2
• Assay Reference Genome Location: Chr.X:116174379 on build GRCh38
• Cytoband: Xq23

Target Gene Details

• Entrez Gene ID: 186
• Gene Name: angiotensin II receptor type 2
• Gene Aliases: AT2, ATGR2, MRX88
• Location: Chr.X:116170705-116174972 on Build GRCh38
• Assay Gene Location: Within Exon 3

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
AGTR2	NM_000686.4	3	2306	NP_000677.2
	XM_011537533.1	2	2204	XP_011535835.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
esv2758886	Chr.X:116093882 - 116232733 on Build GRCh38	Gain	AGTR2

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

G-protein coupled receptor

Gene Ontology Categories:

Process(es)

blood vessel remodeling
regulation of systemic arterial blood pressure by circulatory renin-angiotensin
renin-angiotensin regulation of aldosterone production
vasodilation by angiotensin involved in regulation of systemic arterial blood pressure
brain renin-angiotensin system
cellular sodium ion homeostasis
inflammatory response
cell surface receptor signaling pathway
G-protein coupled receptor signaling pathway
G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger
nitric oxide mediated signal transduction
brain development
regulation of blood pressure
positive regulation of cell proliferation
negative regulation of heart rate
negative regulation of norepinephrine secretion
cerebellar cortex development
negative regulation of cell growth
negative regulation of icosanoid secretion
positive regulation of phosphoprotein phosphatase activity
intracellular signal transduction
regulation of metanephros size
exploration behavior
positive regulation of renal sodium excretion
aldosterone secretion
angiotensin-activated signaling pathway
dopamine biosynthetic process
regulation of transcription factor import into nucleus
negative regulation of blood vessel endothelial cell migration
positive regulation of nitric oxide biosynthetic process
positive regulation of transcription, DNA-templated
positive regulation of vasodilation
negative regulation of fibroblast proliferation
positive regulation of cytokine secretion
positive regulation of nitric-oxide synthase activity
negative regulation of neurotrophin TRK receptor signaling pathway
cell growth involved in cardiac muscle cell development
cellular response to dexamethasone stimulus
positive regulation of metanephric glomerulus development
positive regulation of branching involved in ureteric bud morphogenesis
extracellular negative regulation of signal transduction
positive regulation of extrinsic apoptotic signaling pathway

Function(s)

angiotensin type II receptor activity
protein binding
transcription factor binding
peptide hormone binding
receptor antagonist activity