Hs00156070_cn

• Gene Symbol: IDH3B
• Assay Reference Genome Location: Chr.20:2658391 on build GRCh38
• Cytoband: 20p13

Target Gene Details

• Entrez Gene ID: 3420
• Gene Name: isocitrate dehydrogenase 3 (NAD(+)) beta
• Gene Aliases: RP46
• Location: Chr.20:2658390-2664223 on Build GRCh38
• Assay Gene Location: Overlaps - Exon 13

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
IDH3B	NM_006899.4			NP_008830.2
	NM_174855.3			NP_777280.1
	NR_136344.1
	XM_005260716.1			XP_005260773.1
	AK001905.1			BAA91971.1
	AL050094.1			CAB43266.1
	BC001960.1			AAH01960.1
	BX119223.1
	BX647393.1

Target Gene Details

• Entrez Gene ID: 10528
• Gene Name: NOP56 ribonucleoprotein
• Gene Aliases: NOL5A, SCA36
• Location: Chr.20:2652532-2658393 on Build GRCh38
• Assay Gene Location: Overlaps - Exon 12

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
NOP56	NM_006392.3			NP_006383.2
	NR_027700.2
	AK097186.1
	AK292721.1
	BC004937.1			AAH04937.1
	BX641071.1
	BX647439.1
	BX647513.1
	Y12065.1			CAA72789.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv1057464	Chr.20:2650623 - 2989686 on Build GRCh38	Gain	SNORD86 C20orf141 VPS16 EBF4 NOP56 MIR1292 SNORA51 IDH3B SNORD57 PTPRA SNORD110 PCED1A CPXM1 TMEM239 SNORD56
nsv470535	Chr.20:1948896 - 2780594 on Build GRCh38	Gain	SNORD86 TMC2 LOC727993 EBF4 SNORD119 NOP56 MIR1292 SNORA51 TGM3 IDH3B TGM6 SNRPB SNORD57 SNORD110 STK35 ZNF343 SNORD56 PDYN LOC388780
esv3644998	Chr.20:2148722 - 2690694 on Build GRCh38	Gain	SNORD86 TMC2 SNORD119 NOP56 MIR1292 SNORA51 TGM3 IDH3B TGM6 SNRPB SNORD57 SNORD110 ZNF343 SNORD56 LOC388780
nsv458852	Chr.20:2657933 - 2704278 on Build GRCh38	Loss	EBF4 NOP56 IDH3B

More Information

• Set Membership: Intragenic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

dehydrogenase, RNA metabolism protein

Gene Ontology Categories:

Process(es)

tricarboxylic acid cycle
isocitrate metabolic process
2-oxoglutarate metabolic process
NADH metabolic process
rRNA modification
rRNA processing
cell-cell adhesion

Function(s)

magnesium ion binding
isocitrate dehydrogenase (NAD+) activity
electron carrier activity
NAD binding
RNA binding
protein binding
snoRNA binding
poly(A) RNA binding
cadherin binding involved in cell-cell adhesion
histone methyltransferase binding