Hs00158235_cn

• Gene Symbol: TMC6
• Assay Reference Genome Location: Chr.17:78131522 on build GRCh38
• Cytoband: 17q25.3

Target Gene Details

• Entrez Gene ID: 11322
• Gene Name: transmembrane channel like 6
• Gene Aliases: EV1, EVER1, EVIN1, LAK-4P
• Location: Chr.17:78108775-78132427 on Build GRCh38
• Assay Gene Location: Within Intron 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
TMC6	NM_007267.7			NP_009198.4
	BC023597.2			AAH23597.1
	HY057592.1

Target Gene Details

• Entrez Gene ID: 147138
• Gene Name: transmembrane channel like 8
• Gene Aliases: EV2, EVER2, EVIN2
• Location: Chr.17:78129296-78142968 on Build GRCh38
• Assay Gene Location: Within Exon 2

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
TMC8	NM_152468.4	2	316	NP_689681.2
	XM_011524402.2	2	1794	XP_011522704.1
	XM_011524403.2	2	1793	XP_011522705.1
	XM_011524404.2	2	1793	XP_011522706.1
	XM_011524406.2	2	1796	XP_011522708.1
	XM_011524409.2	2	1798	XP_011522711.1
	XM_011524410.2	2	1796	XP_011522712.1
	XM_011524411.2	2	1796	XP_011522713.1
	XM_017024238.1	2	1795	XP_016879727.1
	XM_017024239.1	2	1795	XP_016879728.1
	XM_017024240.1	2	1795	XP_016879729.1
	XM_017024241.1	2	1794	XP_016879730.1
	XM_017024244.1	2	1796	XP_016879733.1
	AK090478.1	2	276
	AK303499.1	2	315
	AK310623.1	2	318
	AY099358.1	2	306	AAM44454.1
	AY099359.1			AAM44455.1
	AY236500.1			AAP69878.1
	BC110296.1	2	308	AAI10297.1
	BC141865.1	1	160
	DC407759.1	2	318

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv833554	Chr.17:77977426 - 78151914 on Build GRCh38	Gain+Loss	TNRC6C-AS1 TNRC6C C17orf99 TMC8 TMC6
nsv470607	Chr.17:78121280 - 78177341 on Build GRCh38	Loss	C17orf99 TMC8 TK1 TMC6 SYNGR2

More Information

• Set Membership: Intragenic, Exonic, Intronic, Non-exonic, DGV Variation

Gene Ontology Categories:

Process(es)

ion transport
biological_process
regulation of cell growth
negative regulation of protein binding
negative regulation of protein oligomerization
zinc ion homeostasis
regulation of extrinsic apoptotic signaling pathway via death domain receptors

Function(s)

protein binding
receptor binding