Hs00199902_cn

• Gene Symbol: DTX3
• Assay Reference Genome Location: Chr.12:57606483 on build GRCh38
• Cytoband: 12q13.3

Target Gene Details

• Entrez Gene ID: 196403
• Gene Name: deltex E3 ubiquitin ligase 3
• Gene Aliases: RNF154, deltex3
• Location: Chr.12:57604327-57609804 on Build GRCh38
• Assay Gene Location: Overlaps Exon 5 - Intron 5

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
DTX3	NM_001286245.1			NP_001273174.1
	NM_001286246.1			NP_001273175.1
	NM_178502.3			NP_848597.1
	XM_005268697.1			XP_005268754.1
	XM_005268698.1			XP_005268755.1
	XM_005268700.1			XP_005268757.1
	XM_005268703.1			XP_005268760.1
	XM_011538022.2			XP_011536324.1
	AK092085.1			BAC03801.1
	AK094385.1			BAC04344.1
	AK128752.1
	AL831941.1	2	1287	CAD38593.2
	AY225126.1			AAP57520.1
	BC114441.1
	BC114498.1
	DA684401.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv428283	Chr.12:57435950 - 57608085 on Build GRCh38	Gain	DDIT3 MARS KIF5A INHBE INHBC MBD6 MIR616 ARHGAP9 DCTN2 DTX3 PIP4K2C GLI1 MIR6758
nsv559034	Chr.12:57466149 - 57618450 on Build GRCh38	Loss	DDIT3 LOC101927583 MARS KIF5A MBD6 MIR616 ARHGAP9 DCTN2 DTX3 PIP4K2C GLI1 MIR6758 ARHGEF25
nsv482992	Chr.12:56206217 - 57706217 on Build GRCh38	Gain+Loss	IL23A STAT6 SDR9C7 LRP1-AS NXPH4 NAB2 SLC26A10 INHBC SPRYD4 NEMP1 RBMS2 RDH16 OS9 DCTN2 NDUFA4L2 CNPY2 ATP5B HSD17B6 R3HDM2 INHBE SNORD59A LRP1 CS PRIM1 RNF41 HBCBP ARHGAP9 SNORA105C MYO1A DTX3 STAT2 MIR1228 ARHGEF25 LOC101927583 ANKRD52 GLS2 KIF5A PTGES3 SNORD59B SLC39A5 TIMELESS B4GALNT1 MBD6 BAZ2A PAN2 PIP4K2C NABP2 GPR182 TAC3 APOF NACA GLI1 STAC3 ZBTB39 DDIT3 MARS MIR616 COQ10A SHMT2 MIP MIR6758

More Information

• Set Membership: Intragenic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

ubiquitin-protein ligase

Gene Ontology Categories:

Process(es)

Notch signaling pathway
protein ubiquitination

Function(s)

protein binding
zinc ion binding
ligase activity