Hs00201295_cn

• Gene Symbol: PPM1M
• Assay Reference Genome Location: Chr.3:52249928 on build GRCh38
• Cytoband: 3p21.2

Target Gene Details

• Entrez Gene ID: 132160
• Gene Name: protein phosphatase, Mg2+/Mn2+ dependent 1M
• Gene Aliases: PP2C-eta, PP2CE, PP2Ceta
• Location: Chr.3:52245725-52250599 on Build GRCh38
• Assay Gene Location: Within Exon 11

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
PPM1M	NM_001122870.2	9	1160	NP_001116342.1
	NM_144641.3	10	1526	NP_653242.3
	XM_005264879.2	10	1619	XP_005264936.1
	XM_005264880.3	9	1339	XP_005264937.1
	XM_005264881.1	10	1415	XP_005264938.1
	AK056894.1	9	1762	BAB71302.1
	AK096681.1	8	1454	BAC04839.1
	AK129647.1	4	791	BAC85206.1
	AL832484.1	8	1434
	BC009644.1	9	1121	AAH09644.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv834695	Chr.3:52165685 - 52366561 on Build GRCh38	Loss	PPM1M ALAS1 WDR82 DNAH1 TLR9 LOC101929054 GLYCTK TWF2 GLYCTK-AS1 MIRLET7G MIR135A1
nsv508926	Chr.3:52121853 - 52256394 on Build GRCh38	Insertion	PPM1M ALAS1 WDR82 TLR9 LOC101929054 TWF2 POC1A
nsv834694	Chr.3:52144967 - 52301805 on Build GRCh38	Gain	PPM1M ALAS1 WDR82 TLR9 LOC101929054 GLYCTK TWF2 GLYCTK-AS1 MIRLET7G MIR135A1 POC1A
nsv460537	Chr.3:52114217 - 52256534 on Build GRCh38	Loss	PPM1M ALAS1 WDR82 TLR9 LOC101929054 TWF2 POC1A
nsv519445	Chr.3:51970301 - 52333916 on Build GRCh38	Gain+Loss	ABHD14A-ACY1 ABHD14B DNAH1 TLR9 LOC101929054 GLYCTK ABHD14A TWF2 MIR135A1 RPL29 POC1A PPM1M ALAS1 WDR82 ACY1 GLYCTK-AS1 MIRLET7G DUSP7 LINC00696
nsv470572	Chr.3:52089297 - 52316196 on Build GRCh38	Loss	PPM1M ALAS1 WDR82 DNAH1 TLR9 LOC101929054 GLYCTK TWF2 GLYCTK-AS1 MIRLET7G MIR135A1 POC1A

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

protein phosphatase

Gene Ontology Categories:

Process(es)

protein dephosphorylation

Function(s)

CTD phosphatase activity
manganese ion binding