Hs00210345_cn

• Gene Symbol: PARP2
• Assay Reference Genome Location: Chr.14:20343704 on build GRCh38
• Cytoband: 14q11.2

Target Gene Details

• Entrez Gene ID: 10038
• Gene Name: poly(ADP-ribose) polymerase 2
• Gene Aliases: ADPRT2, ADPRTL2, ADPRTL3, ARTD2, PARP-2, pADPRT-2
• Location: Chr.14:20343041-20357904 on Build GRCh38
• Assay Gene Location: Overlaps Exon 1 - Intron 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
PARP2	NM_001042618.1			NP_001036083.1
	NM_005484.3			NP_005475.2
	XM_005267247.3			XP_005267304.1
	XM_017020912.1			XP_016876401.1
	AF085734.1			AAD29857.1
	AJ236912.1			CAB65088.1
	AK001980.1			BAA92017.1
	AK290079.1
	AK300971.1
	DA354586.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
esv23438	Chr.14:20332606 - 20789719 on Build GRCh38	Gain+Loss	RPPH1 RNASE9 PARP2 LOC254028 PNP APEX1 TMEM55B OR6S1 RNASE12 CCNB1IP1 RNASE10 EDDM3A RNASE6 KLHL33 ANG EDDM3B RNASE11 TEP1 TRL-AAG2-3 OSGEP RNASE4
nsv1042025	Chr.14:20319802 - 20349692 on Build GRCh38	Loss	CCNB1IP1 RPPH1 PARP2 SNORD126

More Information

• Set Membership: Intragenic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

DNA metabolism protein

Gene Ontology Categories:

Process(es)

lagging strand elongation
DNA repair
base-excision repair
protein ADP-ribosylation
DNA ligation involved in DNA repair
extrinsic apoptotic signaling pathway

Function(s)

DNA binding
DNA ligase (ATP) activity
NAD+ ADP-ribosyltransferase activity
protein binding