Hs00218348_cn

• Gene Symbol: NFATC4
• Assay Reference Genome Location: Chr.14:24376060 on build GRCh38
• Cytoband: 14q12

Target Gene Details

• Entrez Gene ID: 4776
• Gene Name: nuclear factor of activated T-cells 4
• Gene Aliases: NF-AT3, NF-ATC4, NFAT3
• Location: Chr.14:24366911-24379604 on Build GRCh38
• Assay Gene Location: Overlaps Exon 10 - Intron 10

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
NFATC4	NM_001136022.2			NP_001129494.1
	NM_001198965.1			NP_001185894.1
	NM_001198966.2			NP_001185895.1
	NM_001198967.2			NP_001185896.1
	NM_001288802.1			NP_001275731.1
	NM_001320043.1			NP_001306972.1
	NM_004554.4			NP_004545.2
	XM_011536797.2			XP_011535099.1
	XM_011536798.1			XP_011535100.1
	XM_011536799.2			XP_011535101.1
	AK293185.1
	AK302271.1
	AK310433.1
	AK310445.1
	AK311425.1
	BC008857.2			AAH08857.2
	BC053855.1			AAH53855.1
	EU887632.1
	EU887633.1
	EU887634.1
	EU887635.1
	EU887636.1
	EU887637.1
	EU887638.1
	EU887639.1
	EU887640.1
	EU887641.1
	EU887642.1
	EU887643.1
	EU887644.1
	EU887645.1
	EU887646.1
	EU887647.1
	EU887648.1
	EU887649.1
	EU887650.1
	EU887651.1
	EU887652.1
	EU887653.1
	EU887654.1
	EU887655.1
	L41066.1			AAA79175.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv952819	Chr.14:24367695 - 24377694 on Build GRCh38	Deletion	NFATC4

More Information

• Set Membership: Intragenic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

Rel homology transcription factor

Gene Ontology Categories:

Process(es)

patterning of blood vessels
transcription from RNA polymerase II promoter
inflammatory response
heart development
intrinsic apoptotic signaling pathway in response to DNA damage
negative regulation of Wnt signaling pathway
negative regulation of protein binding
positive regulation of tumor necrosis factor production
calcineurin-NFAT signaling cascade
cellular response to UV
negative regulation of chromatin binding
cellular respiration
positive regulation of transcription from RNA polymerase II promoter
regulation of synaptic plasticity
negative regulation of dendrite morphogenesis
smooth muscle cell differentiation
muscle cell development
cellular response to lithium ion
negative regulation of pri-miRNA transcription from RNA polymerase II promoter
negative regulation of synapse maturation
positive regulation of apoptotic signaling pathway

Function(s)

RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding
transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding
transcription coactivator activity
protein binding
transcription factor binding
peroxisome proliferator activated receptor binding