Hs00227340_cn

• Gene Symbol: ADAMTS15
• Assay Reference Genome Location: Chr.11:130462721 on build GRCh38
• Cytoband: 11q24.3

Target Gene Details

• Entrez Gene ID: 170689
• Gene Name: ADAM metallopeptidase with thrombospondin type 1 motif 15
• Gene Aliases: -
• Location: Chr.11:130448876-130478215 on Build GRCh38
• Assay Gene Location: Within Exon 5

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
ADAMTS15	NM_139055.3	4	1483	NP_620686.1
	XM_005271419.4	4	767	XP_005271476.1
	AJ315733.1	4	1483	CAC86014.1
	BC109114.1	4	1483	AAI09115.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
esv2759871	Chr.11:130099327 - 130472822 on Build GRCh38	Loss	ADAMTS8 ST14 LOC646383 ZBTB44 APLP2 ADAMTS15
nsv508660	Chr.11:130397628 - 130503590 on Build GRCh38	Deletion	ADAMTS8 LOC646383 ADAMTS15

More Information

Additional Information:

For this assay, SNP(s) [rs77956639] are located under a primer or probe sequence. To help evaluate the possible impact of a given SNP on your experiment, please refer to the 1000 Genomes and NCBI dbSNP databases. A higher minor allele frequency in your study population represents a higher risk to assay performance.

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

metalloprotease

Gene Ontology Categories:

Process(es)

proteolysis

Function(s)

metalloendopeptidase activity
heparin binding
zinc ion binding
extracellular matrix binding