Hs00228043_cn

• Gene Symbol: DKK3
• Assay Reference Genome Location: Chr.11:11968437 on build GRCh38
• Cytoband: 11p15.3

Target Gene Details

• Entrez Gene ID: 27122
• Gene Name: dickkopf WNT signaling pathway inhibitor 3
• Gene Aliases: REIC, RIG
• Location: Chr.11:11962996-12009370 on Build GRCh38
• Assay Gene Location: Overlaps Intron 6 - Exon 6

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
DKK3	NM_001018057.1			NP_001018067.1
	NM_013253.4			NP_037385.2
	NM_015881.5			NP_056965.3
	XM_006718178.2			XP_006718241.1
	XM_017017553.1			XP_016873042.1
	XM_017017554.1			XP_016873043.1
	XM_017017555.1			XP_016873044.1
	AB033421.1			BAA85488.1
	AB034203.1			BAA90548.1
	AB057591.1			BAB84360.1
	AF177396.1			AAF02676.1
	AK092979.1
	AK098756.1
	AK225156.1
	AK289897.1
	AK295441.1
	AK295539.1
	AL535720.3
	AY358378.1			AAQ88744.1
	AY587550.1			AAS86757.1
	BC007660.2			AAH07660.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
esv3625386	Chr.11:11950780 - 11971129 on Build GRCh38	Gain	DKK3 USP47
nsv483000	Chr.11:10678454 - 12678453 on Build GRCh38	Loss	CTR9 EIF4G2 MIR6124 GALNT18 MICAL2 ZBED5 LOC101928053 SNORD97 TEAD1 LOC105376554 ZBED5-AS1 DKK3 MIR8070 MIR4299 CSNK2A3 USP47 PARVA MRVI1 MICALCL LOC105376545
nsv832067	Chr.11:11777158 - 11976774 on Build GRCh38	Gain	DKK3 MIR8070 USP47
nsv553544	Chr.11:11956026 - 11977482 on Build GRCh38	Gain	DKK3 USP47

More Information

• Set Membership: Intragenic, Non-exonic, DGV Variation

Gene Ontology Categories:

Process(es)

anatomical structure morphogenesis
Wnt signaling pathway
regulation of transforming growth factor beta receptor signaling pathway
adrenal gland development
negative regulation of aldosterone biosynthetic process
negative regulation of transcription, DNA-templated
negative regulation of canonical Wnt signaling pathway
negative regulation of anti-Mullerian hormone signaling pathway
negative regulation of cortisol biosynthetic process