Hs00228258_cn

• Gene Symbol: SPAST
• Assay Reference Genome Location: Chr.2:32064212 on build GRCh38
• Cytoband: 2p22.3

Target Gene Details

• Entrez Gene ID: 6683
• Gene Name: spastin
• Gene Aliases: ADPSP, FSP2, SPG4
• Location: Chr.2:32063551-32157637 on Build GRCh38
• Assay Gene Location: Overlaps Exon 1 - Intron 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
SPAST	NM_014946.3			NP_055761.2
	NM_199436.1			NP_955468.1
	XM_005264516.4			XP_005264573.1
	XM_011533067.2			XP_011531369.1
	XM_017004777.1			XP_016860266.1
	XM_017004778.1			XP_016860267.1
	AB029006.1			BAA83035.1
	AJ246001.1			CAB60141.1
	BC150260.1

More Information

• Set Membership: Intragenic, Non-exonic, non-DGV Variation

Panther Classification:

Molecular Function -

non-motor microtubule binding protein

Gene Ontology Categories:

Process(es)

mitotic cytokinesis
microtubule bundle formation
ER to Golgi vesicle-mediated transport
axonogenesis
anterograde axonal transport
metabolic process
exit from mitosis
axonal transport of mitochondrion
positive regulation of microtubule depolymerization
cytoplasmic microtubule organization
nuclear envelope reassembly
positive regulation of cytokinesis
cytokinetic process
protein hexamerization
microtubule severing
mitotic spindle disassembly
protein homooligomerization
membrane fission

Function(s)

protein binding
ATP binding
microtubule binding
microtubule-severing ATPase activity
alpha-tubulin binding
beta-tubulin binding