Hs00251701_cn

• Gene Symbol: DBH
• Assay Reference Genome Location: Chr.9:133656612 on build GRCh38
• Cytoband: 9q34.2

Target Gene Details

• Entrez Gene ID: 1621
• Gene Name: dopamine beta-hydroxylase
• Gene Aliases: DBM
• Location: Chr.9:133636363-133659344 on Build GRCh38
• Assay Gene Location: Overlaps Exon 10 - Intron 10

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
DBH	NM_000787.3			NP_000778.3
	BC017174.2			AAH17174.1
	CD014125.1
	X13255.1			CAA31631.1
	X13256.1			CAA31632.1
	Y00096.1			CAA68285.1

Target Gene Details

• Entrez Gene ID: 138948
• Gene Name: DBH antisense RNA 1
• Gene Aliases: NCRNA00118
• Location: Chr.9:133654587-133657408 on Build GRCh38
• Assay Gene Location: Within Intron 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
DBH-AS1	NR_102735.1
	AF129263.1	1	875
	AF129264.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
esv2739138	Chr.9:132727483 - 135521553 on Build GRCh38	Deletion	LOC105376306 LOC101448202 MIR3689D1 SURF6 CELP LOC100130548 MIR3689C C9orf62 COL5A1-AS1 OLFM1 ABO C9orf116 CEL DBH-AS1 FAM163B MIR3689B ADAMTSL2 RXRA MIR3689A DBH SARDH PPP1R26-AS1 MIR548AW MIR3689E LINC00094 SNORD36A SLC2A6 MED22 COL5A1 SNORD24 WDR5 SPACA9 LCN1 MIR3689F MRPS2 FCN1 RPL7A GTF3C5 MIR6877 MIR4669 VAV2 SURF2 SNORD36B LOC101928193 GBGT1 SURF4 RNU6ATAC LOC401557 LOC100996574 REXO4 SNORD36C TMEM8C STKLD1 ADAMTS13 LOC101928525 CACFD1 FCN2 AK8 MIR3689D2 RALGDS GFI1B SURF1 OBP2B TSC1 SNORD141A BRD3 PPP1R26
nsv615640	Chr.9:133650175 - 133663599 on Build GRCh38	Loss	DBH SARDH DBH-AS1
nsv951800	Chr.9:133627979 - 133696678 on Build GRCh38	Deletion	DBH SARDH DBH-AS1
esv3576711	Chr.9:133582804 - 133778331 on Build GRCh38	Gain	FAM163B DBH VAV2 SARDH DBH-AS1

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

hydroxylase, oxidoreductase, metabolite interconversion enzyme

Gene Ontology Categories:

Process(es)

cytokine production
blood vessel remodeling
response to amphetamine
leukocyte mediated immunity
chemical synaptic transmission
memory
locomotory behavior
visual learning
regulation of cell proliferation
homoiothermy
dopamine catabolic process
norepinephrine biosynthetic process
catecholamine biosynthetic process
glucose homeostasis
fear response
maternal behavior
positive regulation of vasoconstriction
behavioral response to ethanol
response to pain
leukocyte migration
oxidation-reduction process
regulation of extrinsic apoptotic signaling pathway

Function(s)

catalytic activity
dopamine beta-monooxygenase activity
copper ion binding
L-ascorbic acid binding