Hs00266235_cn

• Gene Symbol: CFL2
• Assay Reference Genome Location: Chr.14:34712463 on build GRCh38
• Cytoband: 14q13.1

Target Gene Details

• Entrez Gene ID: 1073
• Gene Name: cofilin 2
• Gene Aliases: NEM7
• Location: Chr.14:34710382-34714823 on Build GRCh38
• Assay Gene Location: Within Exon 6

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
CFL2	NM_001243645.1	4	1021	NP_001230574.1
	NM_021914.7	4	1044	NP_068733.1
	NM_138638.4	4	1186	NP_619579.1
	NR_028130.1	4	1043
	NR_028131.1	4	932
	XM_011536363.2	4	982	XP_011534665.1
	AF087867.1	4	939	AAM10495.1
	AF134802.1	4	1055	AAD31280.1
	AF134803.1	4	949	AAD31281.1
	AL117457.1	1	269
	BC011444.1	4	970	AAH11444.1
	BC022364.1	4	1053	AAH22364.1
	BC022876.1	4	1057	AAH22876.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv1041857	Chr.14:34615683 - 34947974 on Build GRCh38	Gain	BAZ1A SNX6 IGBP1P1 CFL2

More Information

Additional Information:

For this assay, SNP(s) [rs116651711] are located under a primer or probe sequence. To help evaluate the possible impact of a given SNP on your experiment, please refer to the 1000 Genomes and NCBI dbSNP databases. A higher minor allele frequency in your study population represents a higher risk to assay performance.

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

non-motor actin binding protein

Gene Ontology Categories:

Process(es)

actin filament depolymerization
positive regulation of actin filament depolymerization
sarcomere organization
muscle cell cellular homeostasis

Function(s)

protein binding
actin filament binding