Hs00274243_cn

• Gene Symbol: OASL
• Assay Reference Genome Location: Chr.12:121020503 on build GRCh38
• Cytoband: 12q24.31

Target Gene Details

• Entrez Gene ID: 8638
• Gene Name: 2'-5'-oligoadenylate synthetase like
• Gene Aliases: OASLd, TRIP-14, TRIP14, p59 OASL, p59-OASL, p59OASL
• Location: Chr.12:121018882-121039242 on Build GRCh38
• Assay Gene Location: Within Exon 6

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
OASL	NM_001261825.1	4	1484	NP_001248754.1
	NM_003733.3	6	1874	NP_003724.1
	NM_198213.2	5	1632	NP_937856.1
	XM_017020140.1			XP_016875629.1
	XM_017020141.1			XP_016875630.1
	AJ225089.1	6	1609	CAA12396.1
	AK023956.1	6	1610
	AK314419.1
	AW069118.1	1	230
	BC117408.1	6	1627
	BC117410.1	6	1627
	BM918192.1	1	229
	JQ792168.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv1039216	Chr.12:120983898 - 121100688 on Build GRCh38	Gain	C12orf43 OASL HNF1A
nsv560454	Chr.12:121019270 - 121307939 on Build GRCh38	Loss	CAMKK2 OASL P2RX7 P2RX4
nsv521928	Chr.12:120603925 - 121356945 on Build GRCh38	Gain	CAMKK2 CABP1 UNC119B ACADS C12orf43 HNF1A-AS1 OASL SPPL3 MLEC HNF1A P2RX7 ANAPC5 MIR4700 XLOC_009911 P2RX4
esv2759917	Chr.12:120978042 - 121147010 on Build GRCh38	Loss	C12orf43 OASL HNF1A P2RX7
nsv832531	Chr.12:121002692 - 121166429 on Build GRCh38	Gain	C12orf43 OASL P2RX7

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

nucleotidyltransferase

Gene Ontology Categories:

Process(es)

response to virus
negative regulation of viral genome replication
defense response to virus
interferon-gamma-mediated signaling pathway
type I interferon signaling pathway

Function(s)

2'-5'-oligoadenylate synthetase activity
DNA binding
double-stranded RNA binding
ATP binding
poly(A) RNA binding
thyroid hormone receptor binding