Hs00281378_cn

• Gene Symbol: TRADD
• Assay Reference Genome Location: Chr.16:67155393 on build GRCh38
• Cytoband: 16q22.1

Target Gene Details

• Entrez Gene ID: 8717
• Gene Name: TNFRSF1A associated via death domain
• Gene Aliases: Hs.89862
• Location: Chr.16:67154185-67159909 on Build GRCh38
• Assay Gene Location: Overlaps Intron 4 - Exon 4

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
TRADD	NM_001323552.1			NP_001310481.1
	NM_003789.3			NP_003780.1
	XM_005256213.3			XP_005256270.1
	XM_017023815.1			XP_016879304.1
	AK090673.1
	AK301593.1
	AK315654.1
	BC004491.2			AAH04491.1
	BG717460.1
	BT006934.1			AAP35580.1
	DA353575.1
	L41690.1			AAA98482.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv522852	Chr.16:67153308 - 68071571 on Build GRCh38	Gain	KIAA0895L PSKH1 NOL3 DPEP3 ZDHHC1 MIR328 E2F4 LCAT DPEP2 KCTD19 LOC107984813 LRRC36 ELMO3 GFOD2 FHOD1 NUTF2 THAP11 TPPP3 TSNAXIP1 CARMIL2 EDC4 LOC105369155 SLC12A4 LOC100131303 PSMB10 FBXL8 CTRL RANBP10 LRRC29 NRN1L SLC9A5 ENKD1 C16orf86 PLEKHG4 CTCF HSF4 LOC100505942 ATP6V0D1 AGRP CENPT PARD6A EXOC3L1 ACD TRADD HSD11B2 DUS2 FAM65A TMEM208 DDX28
nsv827707	Chr.16:67148355 - 67289296 on Build GRCh38	Loss	B3GNT9 EXOC3L1 LOC105369155 KIAA0895L C16orf70 ELMO3 FBXL8 TRADD LRRC29 NOL3 FHOD1 MIR328 SLC9A5 TMEM208 E2F4 PLEKHG4 HSF4
nsv952044	Chr.16:67141198 - 67244397 on Build GRCh38	Deletion	B3GNT9 EXOC3L1 LOC105369155 KIAA0895L C16orf70 ELMO3 FBXL8 TRADD LRRC29 NOL3 FHOD1 MIR328 TMEM208 E2F4 HSF4
nsv524363	Chr.16:67136529 - 68071571 on Build GRCh38	Loss	KIAA0895L PSKH1 NOL3 DPEP3 ZDHHC1 MIR328 E2F4 LCAT DPEP2 KCTD19 LOC107984813 C16orf70 LRRC36 ELMO3 GFOD2 FHOD1 NUTF2 THAP11 TPPP3 TSNAXIP1 CARMIL2 EDC4 LOC105369155 SLC12A4 LOC100131303 PSMB10 FBXL8 CTRL RANBP10 LRRC29 NRN1L SLC9A5 ENKD1 C16orf86 PLEKHG4 CTCF HSF4 LOC100505942 ATP6V0D1 AGRP CENPT PARD6A B3GNT9 EXOC3L1 ACD TRADD HSD11B2 DUS2 FAM65A TMEM208 DDX28

More Information

• Set Membership: Intragenic, Non-exonic, DGV Variation

Gene Ontology Categories:

Process(es)

apoptotic process
activation of cysteine-type endopeptidase activity involved in apoptotic process
signal transduction
I-kappaB kinase/NF-kappaB signaling
extrinsic apoptotic signaling pathway via death domain receptors
regulation of tumor necrosis factor-mediated signaling pathway
regulation of necrotic cell death
tumor necrosis factor-mediated signaling pathway
positive regulation of apoptotic process
positive regulation of I-kappaB kinase/NF-kappaB signaling
positive regulation of NF-kappaB transcription factor activity
protein heterooligomerization
positive regulation of hair follicle development
death-inducing signaling complex assembly
extrinsic apoptotic signaling pathway
activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway
regulation of extrinsic apoptotic signaling pathway via death domain receptors
negative regulation of extrinsic apoptotic signaling pathway via death domain receptors

Function(s)

signal transducer activity
tumor necrosis factor receptor binding
protein binding
kinase binding
protein complex binding
identical protein binding
binding, bridging
death domain binding