Hs00292099_cn

• Gene Symbol: SPIRE1
• Assay Reference Genome Location: Chr.18:12447920 on build GRCh38
• Cytoband: 18p11.21

Target Gene Details

• Entrez Gene ID: 56907
• Gene Name: spire type actin nucleation factor 1
• Gene Aliases: Spir-1
• Location: Chr.18:12446512-12658102 on Build GRCh38
• Assay Gene Location: Within Exon 21

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
SPIRE1	NM_001128626.1	17	4036	NP_001122098.1
	NM_001128627.1	16	3692	NP_001122099.1
	NM_020148.2	16	3994	NP_064533.3
	XM_005258122.4	17	4351	XP_005258179.1
	XM_011525701.1	18	4399	XP_011524003.1
	XM_011525702.1	18	3911	XP_011524004.1
	AB032961.2	17	4088
	AJ277587.1	14	3581	CAB96370.1
	AK025433.1	1	1950

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv1060808	Chr.18:12302793 - 12514418 on Build GRCh38	Gain	TUBB6 SPIRE1 LOC105371998 PRELID3A AFG3L2
nsv576496	Chr.18:12247873 - 12490503 on Build GRCh38	Gain	TUBB6 SPIRE1 LOC105371998 PRELID3A CIDEA AFG3L2
nsv1063125	Chr.18:12046893 - 12918252 on Build GRCh38	Loss	PSMG2 PTPN2 TUBB6 CEP76 PRELID3A AFG3L2 C18orf61 LOC100996333 ANKRD62 SPIRE1 LOC105371998 CIDEA LOC100996324
esv2758714	Chr.18:12240682 - 12499526 on Build GRCh38	Loss	TUBB6 SPIRE1 LOC105371998 PRELID3A CIDEA AFG3L2

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

actin or actin-binding cytoskeletal protein

Gene Ontology Categories:

Process(es)

protein transport
vesicle-mediated transport
actin cytoskeleton organization
cleavage furrow formation
polar body extrusion after meiotic divisions
actin nucleation
intracellular transport
establishment of meiotic spindle localization
formin-nucleated actin cable assembly

Function(s)

actin binding