Hs00304682_cn

• Gene Symbol: TPSG1
• Assay Reference Genome Location: Chr.16:1222277 on build GRCh38
• Cytoband: 16p13.3

Target Gene Details

• Entrez Gene ID: 25823
• Gene Name: tryptase gamma 1
• Gene Aliases: PRSS31, TMT, trpA
• Location: Chr.16:1221651-1226454 on Build GRCh38
• Assay Gene Location: Within Exon 6

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
TPSG1	NM_012467.3	5	578	NP_036599.3
	XM_011522446.2	5	1317	XP_011520748.1
	XM_011522447.2	5	2191	XP_011520749.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
esv2422427	Chr.16:10001 - 2723164 on Build GRCh38	Duplication	LOC105371038 TELO2 BAIAP3 MIR6859-4 FLJ42627 RAB26 SSTR5-AS1 MIR940 CRAMP1 SSTR5 HBQ1 NARFL LOC729652 IGFALS FAHD1 TSC2 TBL3 LOC652276 HAGHL LOC107984876 MIR6511B1 CCDC154 RPS2 STUB1 WDR90 RHBDL1 NME3 LOC107987233 ABCA3 LOC105371045 LOC100134368 GFER MIR3178 CHTF18 PRSS27 LUC7L AXIN1 ATP6V0C TMEM8A HBZ SPSB3 RGS11 SNORA64 HAGH LINC00235 NUBP2 SNORA78 CAPN15 MIR3177 MIR3677 DECR2 RNPS1 CCNF GNPTG CACNA1H PGP PTX4 PDPK1 POLR3K CCDC78 NDUFB10 LOC100287175 NOXO1 TSR3 MIR4516 MIR662 MIR6767 MIR6768 RPL23AP5 LMF1 MSLN SNHG19 CEMP1 TPSAB1 RAB40C METTL26 MAPK8IP3 LOC105371046 FAM173A MRPL28 MRPS34 AMDHD2 NME4 DDX11L10 WFIKKN1 FAM234A ZNF598 TPSB2 NHLRC4 SYNGR3 NPRL3 CASKIN1 E4F1 SOX8 TPSG1 RPL3L MIR4717 METRN FBXL16 MIR3180-5 MIR3176 NPW LOC105371047 JMJD8 IFT140 BRICD5 SNORD60 PRR35 HN1L TRAF7 ABCA17P HBA1 EME2 WDR24 C16orf91 ERVK13-1 C1QTNF8 CLCN7 LMF1-AS1 MLST8 TPSD1 LOC101929280 MEIOB SNRNP25 LINC00254 LOC106660606 KCTD5 SNORA10 UNKL HBA2 RPUSD1 SNHG9 LOC105371184 HS3ST6 NTN3 RNF151 RAB11FIP3 C16orf59 TBC1D24 UBE2I WASIR2 ECI1 NTHL1 PRR25 PKD1 MPG MIR5587 TMEM204 GNG13 PIGQ PDIA2 MSRB1 DNASE1L2 ARHGDIG RHOT2 SLC9A3R2 MIR1225 MCRIP2 HBM RHBDF1 PRSS29P LOC105371049
nsv571109	Chr.16:1205545 - 1287716 on Build GRCh38	Gain	CACNA1H TPSB2 TPSAB1 TPSG1 PRSS29P TPSD1
nsv428316	Chr.16:929650 - 1363252 on Build GRCh38	Gain+Loss	CACNA1H BAIAP3 SSTR5-AS1 TSR3 LMF1 UNKL TPSB2 SOX8 TPSAB1 SSTR5 C1QTNF8 TPSG1 LMF1-AS1 PRSS29P TPSD1 UBE2I GNPTG
nsv1051302	Chr.16:1162523 - 1299208 on Build GRCh38	Gain	CACNA1H TPSB2 TPSAB1 TPSG1 PRSS29P TPSD1
nsv1160327	Chr.16:1063695 - 1222472 on Build GRCh38	Deletion	CACNA1H SSTR5 C1QTNF8 SSTR5-AS1 TPSG1
nsv833117	Chr.16:1217597 - 1318867 on Build GRCh38	Loss	CACNA1H TPSB2 TPSAB1 TPSG1 PRSS29P TPSD1 UBE2I
nsv571101	Chr.16:1078406 - 1287716 on Build GRCh38	Gain	CACNA1H TPSB2 TPSAB1 SSTR5 C1QTNF8 SSTR5-AS1 TPSG1 PRSS29P TPSD1
nsv571108	Chr.16:1202441 - 1283386 on Build GRCh38	Loss	CACNA1H TPSB2 TPSAB1 TPSG1 PRSS29P TPSD1
nsv471066	Chr.16:893361 - 1482836 on Build GRCh38	Loss	CACNA1H BAIAP3 SSTR5-AS1 TSR3 LOC107984876 CCDC154 LMF1 UNKL TPSB2 C16orf91 SOX8 TPSAB1 SSTR5 C1QTNF8 LOC105371045 CLCN7 TPSG1 LMF1-AS1 PRSS29P TPSD1 UBE2I GNPTG
dgv2691n100	Chr.16:1002943 - 1247707 on Build GRCh38	Gain	CACNA1H TPSB2 TPSAB1 SSTR5 C1QTNF8 SSTR5-AS1 TPSG1
nsv952899	Chr.16:1142501 - 1535899 on Build GRCh38	Deletion	CACNA1H TELO2 BAIAP3 LOC105371047 PTX4 IFT140 TSR3 TMEM204 CCDC154 UNKL TPSB2 C16orf91 TPSAB1 LOC105371045 CLCN7 TPSG1 PRSS29P TPSD1 UBE2I GNPTG
nsv571105	Chr.16:1148938 - 1263381 on Build GRCh38	Loss	CACNA1H TPSB2 TPSAB1 TPSG1 PRSS29P TPSD1
nsv571102	Chr.16:1084818 - 1257675 on Build GRCh38	Loss	CACNA1H TPSB2 TPSAB1 C1QTNF8 TPSG1 TPSD1

More Information

Additional Information:

For this assay, SNP(s) [rs143120059] are located under a primer or probe sequence. To help evaluate the possible impact of a given SNP on your experiment, please refer to the 1000 Genomes and NCBI dbSNP databases. A higher minor allele frequency in your study population represents a higher risk to assay performance.

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

serine protease

Gene Ontology Categories:

Process(es)

proteolysis

Function(s)

serine-type endopeptidase activity
serine-type peptidase activity